High Resolution E-Jet Printed Temperature Sensor on Artificial Skin

Vuorinen, Tommi; Laurila, Mika-Matti; Mangayil, Rahul; Karp, Matti; Mäntysalo, Matti

doi:10.1007/978-981-10-5122-7_210

Cited by 18 publications

(21 citation statements)

References 13 publications

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“…This is because the overall structure of the wound dressing can be precisely designed to fit a specific purpose; be it specialised drug loading, that requires an extremely precise pore size, or the development of wound dressings with incorporated biosensors, which would allow the wound dressing to provide clear indications of potential infections or the current progress of healing [ 137 ]. This can be achieved by combining light-sensitive pH materials into the matrix that will fluoresce under UV light, according to the pH of the wound, as the cellulose dressing is transparent, which can be done without having to remove the dressing and thus allows the healing process to be unhindered [ 138 , 139 , 140 ].…”

Section: Limitations and Future Advancementsmentioning

confidence: 99%

Recent Advances and Applications of Bacterial Cellulose in Biomedicine

et al. 2021

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Bacterial cellulose (BC) is an extracellular polymer produced by Komagateibacter xylinus, which has been shown to possess a multitude of properties, which makes it innately useful as a next-generation biopolymer. The structure of BC is comprised of glucose monomer units polymerised by cellulose synthase in β-1-4 glucan chains which form uniaxially orientated BC fibril bundles which measure 3–8 nm in diameter. BC is chemically identical to vegetal cellulose. However, when BC is compared with other natural or synthetic analogues, it shows a much higher performance in biomedical applications, potable treatment, nano-filters and functional applications. The main reason for this superiority is due to the high level of chemical purity, nano-fibrillar matrix and crystallinity. Upon using BC as a carrier or scaffold with other materials, unique and novel characteristics can be observed, which are all relatable to the features of BC. These properties, which include high tensile strength, high water holding capabilities and microfibrillar matrices, coupled with the overall physicochemical assets of bacterial cellulose makes it an ideal candidate for further scientific research into biopolymer development. This review thoroughly explores several areas in which BC is being investigated, ranging from biomedical applications to electronic applications, with a focus on the use as a next-generation wound dressing. The purpose of this review is to consolidate and discuss the most recent advancements in the applications of bacterial cellulose, primarily in biomedicine, but also in biotechnology.

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Section: Limitations and Future Advancementsmentioning

confidence: 99%

Recent Advances and Applications of Bacterial Cellulose in Biomedicine

et al. 2021

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“…Furthermore, BC benefits in high level of purity and crystallinity (Lee et al 2014). Owing to this, BC is extensively researched for its use in various applications (Mangayil et al 2017;Vuorinen et al 2018;Wang et al 2019). However, its widespread application is hindered due to low production metrics such as yield and titer.…”

Section: Introductionmentioning

confidence: 99%

Characterization of a novel bacterial cellulose producer for the production of eco-friendly piezoelectric-responsive films from a minimal medium containing waste carbon

et al. 2020

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Bacterial cellulose (BC) is a biodegradable polymer that benefits in purity, crystallinity and superior optical, structural and mechanical properties. Such properties facilitate BC to replace the conventional non-biodegradable materials used, for instance, in sensing applications. However, BC production is largely conducted in conventional medium containing model substrates and complex carbon-containing compounds. Aiming towards the production of eco-friendly piezoelectric-responsive BC films, we isolated and characterized a novel bacterial strain affiliated to Komagataeibacter rhaeticus. The K. rhaeticus ENS9a strain synthesized BC in minimal medium containing crude glycerol, generating a titer of 2.9 ± 0.3 g/L BC. This is, to the best of our knowledge, the highest BC titer reported from an unoptimized minimal medium containing crude glycerol. Interestingly, the films prepared from crude glycerol showed normal force and bending mode sensitivities of 6–11 pC/N and 40–71 pC/N, respectively, demonstrating a green platform to address both bioprocess waste valorization and implementation of cellulose-based alternatives for the non-sustainable and non-biodegradable materials, such as fluoropolymers or lead containing piezoceramics, used in sensing applications. In silico genome analysis predicted genes partaking in carbohydrate metabolism, BC biogenesis, and nitrogen fixation/regulation. Graphic abstract

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“…Also, the affordability requirement has been solved by employing solution processed materials and additive fabrication technologies such as inkjet [8], screen [11], and gravure printing [12] or spin coating [13] and impregnation [14]. As an additional benefit, the use of additive fabrication technologies enables fabrication of conformable health patches and temporary tattoos [15] [16] which have been previously demonstrated for measuring other vital signs such as ECG [17], pulse oximetry [18], and temperature [19]. In the future, additive fabrication technologies could also enable the integration of the whole measurement system on a single foil in cost effective manner [20] thereby allowing the patient to use the device without the need for professional help.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Printed P(VDF-TrFE) Pressure Sensor Signal Quality in Arterial Pulse Wave Measurement

et al. 2019

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In this contribution, we evaluate the performance of an additively fabricated piezoelectric poly(vinylidenefluoride-cotrifluoroethylene) (P(VDF-TrFE)) based dynamic pressure sensor in non-invasive arterial pulse wave (PW) measurement. Additively fabricated piezoelectric sensors have high potential for the realization of affordable and unobtrusive PW measurement systems which could enable the long-term monitoring of patients with cardiovascular diseases (CVDs). However, the accuracy and reliability of such sensors have not been extensively studied before. We propose an additive fabrication process for a P(VDF-TrFE) PW-sensor, measure PW from the radial artery at the wrist from 22 healthy volunteer subjects, calculate clinically relevant parameters based on the PW waveform and compare their values to the values obtained from concurrent measurement with an electromechanical film (EMFi) based reference sensor, used earlier in several clinical studies. We show that the signals recorded with the two sensors, as well as the radial augmentation index (rAIx) and the stiffness index (SI) calculated from them, are in good agreement with each other. These results demonstrate that the additively fabricated P(VDF-TrFE) PW sensors can reach a suitable level of accuracy and reliability for clinical use.Index Terms-Printed electronics, pulse wave measurement, radial artery, piezoelectric dynamic pressure sensor, P(VDF-TrFE), electret material, EMFi Korkeakoulunkatu 3, 33720, Tampere, Finland. M.-M. Laurila is the

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High Resolution E-Jet Printed Temperature Sensor on Artificial Skin

Cited by 18 publications

References 13 publications

Recent Advances and Applications of Bacterial Cellulose in Biomedicine

Recent Advances and Applications of Bacterial Cellulose in Biomedicine

Characterization of a novel bacterial cellulose producer for the production of eco-friendly piezoelectric-responsive films from a minimal medium containing waste carbon

Evaluation of Printed P(VDF-TrFE) Pressure Sensor Signal Quality in Arterial Pulse Wave Measurement

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