“…The ChestX-ray image of a patient needs to be read by a senior radiologist for at least 10 min to make a diagnosis and different doctors can make inconsistent diagnoses of the same ChestX-ray image, which means that the results are affected by the cognitive ability of the radiologist, subjective experience, fatigue and other factors [2]. Computer-aided diagnosis (CAD) can overcome the deficiencies of radiologists, make Recently, benefitting from deep learning techniques [6], computer vision [7] has had remarkable success in the fields of target detection [8], image classification [9,10] and image inpainting [11], for example. This notable progress has led to the development of many medical image processing applications, including disease classification [12], lesion detection or segmentation [13][14][15], registration [16], image annotation [17,18] as well as other examples [19].…”