High-resolution real-time sonography of the parathyroid.

Simeone, JF; Daniels, Gilbert H.; Müeller, Peter R.; Maloof, Farahe; vanSonnenberg, Eric; Hall, DA; O’Connell, Robert S.; Ferrucci, Joseph T.; Wittenberg, J

doi:10.1148/radiology.141.3.7302232

Cited by 132 publications

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“…9) but the majority resembles the atypical parathyroid adeno-mas with an irregular interior structure. The varying echodensity of thyroid nodules and the similarity to parathyroid lesions probably explain the reduced success rate of parathyroid ultrasonography in patients with a nodular goitre (2,3,8,9,11). A satisfactory discrimination between especially heterogeneous parathyroid adenomas and thyroid noduli requires ultrasonically guided fine needle biopsies with a discriminative staining of the needle aspirate (7).…”

Section: Discussionmentioning

confidence: 99%

“…The accuracy of ultrasound in demonstrating enlarged parathyroid glands has been documented and the pitfalls of the technique are becoming evident (2,(5)(6)(7)(8)(9)(10)(11). Failures to locate parathyroid lesions occur especially in patients with a multinodular goitre and in those with small or moderately enlarged parathyroid glands situated in positions difficult to investigate by ultrasound (8).…”

mentioning

confidence: 99%

“…Failures to locate parathyroid lesions occur especially in patients with a multinodular goitre and in those with small or moderately enlarged parathyroid glands situated in positions difficult to investigate by ultrasound (8). It may be difficult to ultrasonically differentiate a parathyroid tumour from lymph nodes and dorsally projecting thyroid nodules (5,6,8,11). In order to increase the possibility of identification we have systematically investigated the ultrasonic characteristics of preoperatively demonstrated and surgically confirmed adenomatous and hyperplastic parathyroid glands.…”

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confidence: 99%

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Ultrasonic Appearance of Adenomatous and Hyperplastic Parathyroid Glands

Rastad¹,

Fransson²,

Lindgren³

et al. 1984

Acta Radiologica. Diagnosis

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An investigation was made of the sonographic and histopathologic characteristics of 27 parathyroid adenomas and II primary and secondary hyperplastic parathyroid glands demonstrated by ultrasound before surgical confirmation. All the hyperplastic glands and 21 of the adenomas had a homogeneously sonolucent interior structure and a smooth periphery. The adenomas and hyperplastic glands were sonographically indistinguishable except for 5 large adenomas which had areas of varying echodensity and an irregularly nodulated periphery. The ultrasonically inhomogeneous adenomas were histopathologically more heterogeneous with asymmetric, nodular enlargement. One patient had a cystic adenoma. The results are discussed in relation to the ultrasonic appearance of thyroid noduli and lymph nodes being the main source of errors in parathyroid ultrasonography.

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%

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confidence: 99%

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Ultrasonic Appearance of Adenomatous and Hyperplastic Parathyroid Glands

Rastad¹,

Fransson²,

Lindgren³

et al. 1984

Acta Radiologica. Diagnosis

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“…Worthy of note is that preoperative ultrasonography in the present cases (Cases 3 and 4) revealed enlarged parathyroid glands as hyperechoic lesions. This hyperechogenicity of the tumor appears to be characteristic of lipoadenoma, because echogenicity of parathyroid neoplasma is consistently less than that of the surrounding normal thyroid tissue (Simione et al, 1981;Reading et al, 1982). We used ultrasonography as the first choice in preoperative localization studies in 103 patients with primary hyperparathyroidism since 1983.…”

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confidence: 99%

Functioning Parathyroid Lipoadenoma. Report of Four Cases: Clinicopathological and Ultrasonographic Features.

et al. 1989

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Functioning parathyroid lipoadenoma (hamartoma) composed of abundant adipose or myxomatous stroma and epithelial cell nests is an unusual cause of primary hyperparathyroidism.We report herein four new cases. None of them belongs in the category of multiple endocrine neoplasia or familial hyperparathyroidism.The clinical manifestations and the laboratory findings are indistinguishable from those of the usual forms of primary hyperparathyroidism.Ultrasonography of the neck demonstrated an enlarged parathyroid gland as a hyperechoic mass in the two patients tested.At operation in each case, a single enlarged gland was found and resected, the weight being 3, 0.3, 0.45 and 1g, respectively. The patients are normocalcemic 1 to 10 years after surgery. Pathological examination disclosed that the lesions were consistent with lipoadenoma or its variants. On reviewing 20 cases of functioning lipoadenoma which were reported in the literature, including the present cases, we found that the size of the tumors varied and a functioning lipoadenoma is hence by no means unusually large as previously reported.Without knowledge of this specific clinicopathologic entity, the lesion may be overlooked at the preoperative localization study and misdiagnosed as a normal or hyperplastic parathyroid.

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“…Sometimes the necessary facilities may not be available [4]. Recently, ultrasound have been employed in localizing abnormal parathyroid glands in adults with primary hyperparathyroidism [3,4,5]. In patients younger than 15 years of age hyperparathyroidism is frequently caused by a large adenoma [1,6].…”

Section: Discussionmentioning

confidence: 99%

Preoperative ultrasonographic diagnosis of a parathyroid adenoma in a child

Rodríguez-Cueto¹,

Manzano-Sierra²,

Villalpando³

1984

Pediatr Radiol

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The case of a young boy with primary hyperparathyroidism due to an adenoma is reported. The tumor was localized by ultrasonography, and a close correlation between the image and the surgical findings was found. Since primary hyperparathyroidism in children under 15 years of age is frequently due to adenomata larger than 1.5 cm it is suggested that ultrasonography of the neck should be included in the work-up of every children suspected to have this pathology.

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High-resolution real-time sonography of the parathyroid.

Cited by 132 publications

References 0 publications

Ultrasonic Appearance of Adenomatous and Hyperplastic Parathyroid Glands

Ultrasonic Appearance of Adenomatous and Hyperplastic Parathyroid Glands

Functioning Parathyroid Lipoadenoma. Report of Four Cases: Clinicopathological and Ultrasonographic Features.

Preoperative ultrasonographic diagnosis of a parathyroid adenoma in a child

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