High resolution skin colorimetry, strain mapping and mechanobiology

Devillers, Céline; Piérard-Franchimont, C; Schreder, Anelavre; Docquier, Valerie; Pierard, Gérald

doi:10.1111/j.1468-2494.2009.00562.x

Cited by 10 publications

(11 citation statements)

References 16 publications

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“…Formulations FB3 and FP3 were analyzed using a 25 mm probe while the other formulations were analyzed with a 13 mm probe. between green and red and b* ranging between blue and yellow (Devillers et al, 2010). From the observations in Table III there is no consistent variation of any parameter of the L*a*b* color space after submitting the samples to thermal stress.…”

Section: Thermal Stability Testmentioning

confidence: 85%

Characterization and stability studies of emulsion systems containing pumice

Estanqueiro

Conceição

Amaral

et al. 2014

Braz. J. Pharm. Sci.

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Emulsions are the most common form of skin care products. However, these systems may exhibit some instability. Therefore, when developing emulsions for topical application it is interesting to verify whether they have suitable physical and mechanical characteristics and further assess their stability. The aim of this work was to study the stability of emulsion systems, which varied in the proportion of the emulsifying agent cetearyl alcohol (and) sodium lauryl sulfate (and) sodium cetearyl sulfate (LSX), the nature of the oily phase (decyl oleate, cyclomethicone or dimethicone) and the presence or absence of pumice (5% w/w). While maintaining the samples at room temperature, rheology studies, texture analysis and microscopic observation of formulations with and without pumice were performed. Samples were also submitted to an accelerated stability study by centrifugation and to a thermal stress test. Through the testing, it was found that the amount of emulsifying agent affects the consistency and textural properties such as firmness and adhesiveness. So, formulations containing LSX (5% w/w) and decyl oleate or dimethicone as oily phase had a better consistency and remained stable with time, so exhibited the best features to be used for skin care products.Uniterms: Emulsions/topical use/stability study. Emulsions/topical use/characterization. Pumice/presence in emulsions. Emulsions/texture. Emulsions/rheology. Emulsions/spreadability.Emulsões são a forma de apresentação mais comum dos produtos para aplicação na pele. No entanto estes sistemas podem exibir alguma instabilidade. Por esta razão, quando do desenvolvimento de emulsões para aplicação tópica é importante verificar se estas apresentam propriedades físicas ou mecânicas adequadas e avaliar a sua estabilidade. O objetivo deste trabalho consistiu no estudo da estabilidade de emulsões, cujas variações entre elas foi a proporção de agente emulsificante álcool estearílico (mais) laurilsulfato de sódio (mais) estearilsulfato de sódio (LSX), a natureza da fase oleosa (decil oleato, ciclometicona ou dimeticona) e a presença ou ausência de pedra-pomes (5% m/m). Mantendo as amostras à mesma temperatura, realizaram-se o estudo da reologia, a análise de textura e observação microscópica das formulações com e sem pedra-pomes. Amostras foram, também, submetidas a estudo de estabilidade acelerada por centrifugação e a ensaio de estresse térmico. Através dos testes realizados, constatou-se que a quantidade de agente emulsificante influencia a consistência e as propriedades de textura, como a firmeza e a adesividade. As formulações contendo LSX (5% m/m) e decil oleato ou dimeticona como fase oleosa exibiram melhores caraterísticas como produtos para aplicação na pele, uma vez que estas formulações apresentaram menor firmeza e consistência e permaneceram estáveis com o tempo.

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Section: Thermal Stability Testmentioning

confidence: 85%

Characterization and stability studies of emulsion systems containing pumice

Estanqueiro

Conceição

Amaral

et al. 2014

Braz. J. Pharm. Sci.

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“…This is an important finding from a participant perspective as this suggests that although breast skin strain may not be related to pain, it may still be relevant to skin damage and breast ptosis. 16 17 However, the subjectivity of pain ratings, large SD across participants and very low breast pain ratings during walking (<0.75 out of 10) question the sensitivity of the pain scoring system. Considering participant characteristics, breast volume, BMI and bust circumference displayed the strongest and most prevalent relationships with peak breast skin strain/strain rate.…”

Section: Discussionmentioning

confidence: 99%

“… 14 15 However, the measurement of breast skin strain is important as breast ptosis (sag) may be related to mechanical strain on breast skin, with mechanical failure of skin possibly manifesting in stretch marks ( striae distensae ). 16 17 …”

Section: Introductionmentioning

confidence: 99%

Do static and dynamic activities induce potentially damaging breast skin strain?

Norris

Mills

Sanchez

et al. 2020

BMJ Open Sport Exerc Med

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Background/AimThis study aimed to quantify breast skin strain and strain rate and the effect of support garments at reducing strain and to determine characteristics that correlate with strain during static and dynamic activity.Methods39 women (UK size 32C to 36G) had electromagnetic sensors applied to their breast skin. Sensor coordinates were recorded while standing, walking, running, in no, low and high breast support conditions, plus bare-breasted in the estimated neutral position to calculate strain. Relative breast coordinates and 35 inter-sensor distances identified peak breast skin strain (%) and strain rate (%·s-1), which were then correlated with nipple kinematics, breast pain and participant characteristics.ResultsMean peak breast skin strain was generally <60% during standing, walking and running; however, some individuals exhibited 93% strain in bare-breasted running. Compared with low support, high support did not further reduce strain during standing and walking. Peak breast skin strain/strain rate location was longitudinal, in lateral and medial breast regions and displayed strong correlations with breast volume, body mass index and bust circumference.ConclusionStatic and dynamic activity did not result in excessive breast skin strain, suggesting low risk of skin damage. However, during running, some individuals experienced excessive skin strains (up to 93%) and strain rates (up to 1258%·s-1). Breast skin strain/strain rate location suggests lift is required in the lateral and medial bra cup to reduce strain, particularly in larger breast volumes due to increased skin strain risk.

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“…7 Vascular changes occur which contribute to the red and erythematous appearance of striae rubrae. 9 Additionally, in striae rubrae, collagen fibres become thicker, more densely packed, are arranged in a parallel pattern and show a reduction in elastic fibres. 6,10 Conversely, striae albae have less vascularity and tend to be very pale in colour.…”

Section: Introductionmentioning

confidence: 99%

“…Gradual atrophy of the epidermis has been noted including loss of rete ridges . Vascular changes occur which contribute to the red and erythematous appearance of striae rubrae . Additionally, in striae rubrae, collagen fibres become thicker, more densely packed, are arranged in a parallel pattern and show a reduction in elastic fibres .…”

Section: Introductionmentioning

confidence: 99%

Topical management of striae distensae (stretch marks): prevention and therapy of striae rubrae and albae

Uddin

McGeorge²,

Bayat

2015

Acad Dermatol Venereol

104

105

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Striae distensae (SD) are common dermal lesions, with significant physical and psychological impact. Many therapeutic modalities are available but none can completely eradicate SD. The most common therapy is the application of topicals used both therapeutically and prophylactically. Even though there are many commercially available topical products, not all have sufficient level of evidence to support their continued use in SD. The aim here was to assess the evidence for the use of topicals in SD and to propose a structured approach in managing SD. A systematic search of published literature and manufacturer website information for topicals in SD was carried out. The results showed that there are few studies (n = 11) which investigate the efficacy of topicals in management of SD. Trofolastin and Alphastria creams demonstrated level‐2 evidence of positive results for their prophylactic use in SD. Additionally, tretinoin used therapeutically showed varying results whilst cocoa butter and olive oil did not demonstrate any effect. Overall, there is a distinct lack of evidence for each topical formulation. The majority of topicals failed to mention their effect on early vs. later stages of SD (striae rubrae compared to striae albae) and their role in both prevention and treatment. In conclusion, there is no topical formulation, which is shown to be most effective in eradicating or improving SD. A structured approach in identification and targeted management of symptoms and signs with the appropriate topical is required. Randomized controlled trials are necessary to assess the efficacy of topical products for treatment and prevention of different stages of SD.

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High resolution skin colorimetry, strain mapping and mechanobiology

Cited by 10 publications

References 16 publications

Characterization and stability studies of emulsion systems containing pumice

Characterization and stability studies of emulsion systems containing pumice

Do static and dynamic activities induce potentially damaging breast skin strain?

Topical management of striae distensae (stretch marks): prevention and therapy of striae rubrae and albae

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