High-resolution ultrasound imaging of skin involvement in systemic sclerosis: a systematic review

Dźwigała, Monika; Sobolewski, Piotr; Maślińska, Maria; Yurtsever, Ida; Szymańska, Elżbieta; Walecka, Irena

doi:10.1007/s00296-020-04761-8

Cited by 10 publications

(11 citation statements)

References 19 publications

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“…During the last decade, the applicability of US testing among patients with SSc has been researched to find a tool for the assessment of skin involvement [15][16][17][18][19][20][21][22][23][24]. Several studies have shown that US-SWE can be used to quantitatively characterize the degree of skin involvement among patients with systemic sclerosis [15,20,21].…”

Section: Discussionmentioning

confidence: 99%

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Elastography as a possible useful method of assessment of skin involvement in systemic sclerosis

Sobolewski¹,

Dźwigała²,

Zakrzewski³

et al. 2022

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Introduction: Scleroderma (Sc) is a connective tissue disorder associated with internal organ involvement, increased mortality, and unknown pathogenesis. It has been found that the more extensive the skin involvement the more severe internal organ manifestations and increased disability. The Rodnan skin score (RSS) is one of the established methods to examine skin thickness among patients with Sc. Due to RSS limitations, for instance, lack of detection of subclinical changes, a new tool is needed for the evaluation of Sc. In recent studies, shear wave elastography (SWE) has been examined as a potential tool to assess skin involvement through the evaluation of skin strain. Aim: To verify whether elastography is a reliable method to examine Sc progression and possibly provide one useful site to perform the examination -as an easy, cheap, and reliable examination tool. Material and methods: Forty Sc patients were examined, and 28 healthy individuals were recruited for the control group. Among the patients and control group, skin thickness was assessed using the RSS and skin strain measurements using elastography in 20 body locations. Results: SWE in the right-hand finger can be treated as an important diagnostic indicator of the severity of Sc. Conclusions: SWE is a reliable method for evaluating skin involvement among patients with systemic sclerosis (SSc). Right finger measurements correlate positively with Rodnan's results and can be a predictor of the severity of SSc. This study found SWE to be a reliable method for examining SSc progression and possibly one useful site for the examination.

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Section: Discussionmentioning

confidence: 99%

“…Each area is added together to give an overall result ranging from 0 (no hardening) to 51 (severe hardening of the skin in all 17 areas). The RSS score divides the severity of skin lesions into: mild (1-14), moderate (15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29), severe (30-39), or terminal (≥ 40).…”

Section: Introductionmentioning

confidence: 99%

Elastography as a possible useful method of assessment of skin involvement in systemic sclerosis

Sobolewski¹,

Dźwigała²,

Zakrzewski³

et al. 2022

pdia

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“…Moreover, UHFUS could be used to evaluate the modification of nail structures and thickness in psoriasis. 49,50 In bedridden patients, UHFUS could allow to evaluate of the skin tissue in the lesioned and peri-lesioned area and the small vascular structures to monitor the premature cutaneous deterioration, and to evaluate the disease progression and therapeutic responses. 51 In cutaneous tumor lesions, UFHUS could allow the differential diagnosis between benign and malignant lesions, and, in the latter, it can provide the depth of skin infiltration allowing for individualized surgical treatment.…”

Section: Discussionmentioning

confidence: 99%

“…In scleroderma or in diabetic patients, UHFUS provides a quantitative and reliable assessment of the thickness of the different cutaneous layer and could evaluate the morphea, the cutaneous lesion of scleroderma, allowing to differentiate it from other skin diseases without the use of biopsy. Moreover, UHFUS could be used to evaluate the modification of nail structures and thickness in psoriasis 49,50 . In bedridden patients, UHFUS could allow to evaluate of the skin tissue in the lesioned and peri‐lesioned area and the small vascular structures to monitor the premature cutaneous deterioration, and to evaluate the disease progression and therapeutic responses 51 .…”

Section: Discussionmentioning

confidence: 99%

Clinical application of ultra‐high frequency ultrasound: Discovering a new imaging frontier

Fogante

Carboni

Argalia

2022

J of Clinical Ultrasound

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The ultra‐high frequency ultrasound (UHFUS) is characterized by the use of probes between 30 and 100 MHz. This technology has recently been introduced in clinical practice and represents an opportunity for the diagnosis of numerous pathologies. The high spatial resolution of UHFUS, up to 30 μ in pixel size, allows to study the pathological modifications and to guide microsurgery treatments in anatomical body structures not evaluable by conventional HFUS. The aim of this work is to provide a review of the literature on the current clinical applications of UHFUS and to discuss its added role in different clinical settings.

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“…Dermal thickness has been shown to be inversely corelated with blood perfusion. Additionally, US elastography has been shown to be of value in the evaluation of the skin in SSc [ 23 , 25 , 26 , 27 , 28 , 29 ]. Claw hands ( Figure 3 A), thin lips, sharp nose, and a characteristic “mouse face” appearance can result from this [ 23 ].…”

Section: Autoimmune/inflammatory Disorders and Vasculitidesmentioning

confidence: 99%

Imaging More than Skin-Deep: Radiologic and Dermatologic Presentations of Systemic Disorders

et al. 2022

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Background: Cutaneous manifestations of systemic diseases are diverse and sometimes precede more serious diseases and symptomatology. Similarly, radiologic imaging plays a key role in early diagnosis and determination of the extent of systemic involvement. Simultaneous awareness of skin and imaging manifestations can help the radiologist to narrow down differential diagnosis even if imaging findings are nonspecific. Aims: To improve diagnostic accuracy and patient care, it is important that clinicians and radiologists be familiar with both cutaneous and radiologic features of various systemic disorders. This article reviews cutaneous manifestations and imaging findings of commonly encountered systemic diseases. Conclusions: Familiarity with the most disease-specific skin lesions help the radiologist pinpoint a specific diagnosis and consequently, in preventing unnecessary invasive workups and contributing to improved patient care.

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High-resolution ultrasound imaging of skin involvement in systemic sclerosis: a systematic review

Cited by 10 publications

References 19 publications

Elastography as a possible useful method of assessment of skin involvement in systemic sclerosis

Elastography as a possible useful method of assessment of skin involvement in systemic sclerosis

Clinical application of ultra‐high frequency ultrasound: Discovering a new imaging frontier

Imaging More than Skin-Deep: Radiologic and Dermatologic Presentations of Systemic Disorders

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