High sensitivity photonic crystal biosensor incorporating nanorod structures for enhanced surface area

Zhang, Wei; Ganesh, Nikhil; Block, Ian D.; Cunningham, Brian T.

doi:10.1016/j.snb.2007.11.017

Cited by 100 publications

(40 citation statements)

References 33 publications

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“…The PCs used in their works are nanostructures composed of a periodically modulated low refractive index plastic/SiO 2 surface structure that is coated with a high refractive index dielectric [81,82].…”

Section: Pcs-assisted High Effective Fluorescence Sensorsmentioning

confidence: 99%

High effective sensors based on photonic crystals

Song

2010

Front. Chem. China

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Photonic crystals have been extensively studied as high effective sensors for environmental monitoring and chemical and biological detections. This paper reviews recent achievements on photonic crystal sensors. Especially, the band gap responsiveness and the ability in amplifying spontaneous emission are demonstrated in the reported photonic crystal monitors/sensors. They are of great importance for optical monitors/sensors visualized by the naked eye and sensors based on fluorescence applications. The photonic crystal sensors are promising for low-cost and high effective sensors and detection methods, although challenges still exist in practical applications.

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Section: Pcs-assisted High Effective Fluorescence Sensorsmentioning

confidence: 99%

High effective sensors based on photonic crystals

Song

2010

Front. Chem. China

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“…Photonic crystals find various applications in single-mode waveguides [2], super-prisms [3], perfect lenses [4], and biosensors [5]. These applications would be significantly improved if the band structure of the crystal could be tuned.…”

Section: Introductionmentioning

confidence: 99%

Influence of the Heat Treatment on the Band Gaps in the Biopolymer Photonic Crystals

2009

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1D photonic crystal was fabricated in a dichromate-sensitized biopolymer using holography method. The effects of the temperature of the photonic crystal layer on the center of photonic band gaps were studied. We showed that the central wavelength of the band gap can be tuned by heating the photonic crystal layer. By applying such heat treatment, tuning of the position of the band gap for about 80 nm was obtained.

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“…Because the features of the nanorods are far smaller than the resonant wavelength, the nanorod layer does not cause scattering or absorption that results in extinguishing the resonance. 14 Compared with non-porous PCs, the porous PCs do not result in significant broadening or shortening of the resonant peak, which is vital to establishing lasing action in the ECL system.…”

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confidence: 99%

“…12 Both sensors undergo the same three-step assay to immobilize the protein CA II onto the surface, which has been described in previously published work. 12,14 Each of the sensor surface chemistry preparation steps, in which the sensors are treated in sequence with polyvinylamine (PVA, provided by SRU Biosystems Inc.)-Glutaraldehyde (GA), and CA II generates $4Â larger laser wavelength value (LWV) shifts in porous PCs as compared to non-porous PCs (Fig. 3(a)).…”

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confidence: 99%

Porous photonic crystal external cavity laser biosensor

Huang

Peh

Hergenrother

et al. 2016

Applied Physics Letters

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We report the design, fabrication, and testing of a photonic crystal (PC) biosensor structure that incorporates a porous high refractive index TiO 2 dielectric film that enables immobilization of capture proteins within an enhanced surface-area volume that spatially overlaps with the regions of resonant electromagnetic fields where biomolecular binding can produce the greatest shifts in photonic crystal resonant wavelength. Despite the nanoscale porosity of the sensor structure, the PC slab exhibits narrowband and high efficiency resonant reflection, enabling the structure to serve as a wavelength-tunable element of an external cavity laser. In the context of sensing small molecule interactions with much larger immobilized proteins, we demonstrate that the porous structure provides 3.7Â larger biosensor signals than an equivalent nonporous structure, while the external cavity laser (ECL) detection method provides capability for sensing picometer-scale shifts in the PC resonant wavelength caused by small molecule binding. The porous ECL achieves a record high figure of merit for label-free optical biosensors. Published by AIP Publishing.

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High sensitivity photonic crystal biosensor incorporating nanorod structures for enhanced surface area

Cited by 100 publications

References 33 publications

High effective sensors based on photonic crystals

High effective sensors based on photonic crystals

Influence of the Heat Treatment on the Band Gaps in the Biopolymer Photonic Crystals

Porous photonic crystal external cavity laser biosensor

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