2012
DOI: 10.1016/j.cep.2012.04.004
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High shear mixers: A review of typical applications and studies on power draw, flow pattern, energy dissipation and transfer properties

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Cited by 178 publications
(112 citation statements)
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“…High shear mixer (HSM), which has been widely utilized in fine dispersions and uniform reactive mixing process due to their highly mass and heat transfer speeds than conventional mechanically impellers [32][33][34][35][36]. Recently, HSM has been adopted to control the crystal polymorph of apixaban (an anticoagulant for the prevention of venous thromboembolism) [37] and BMS-A (a potential drug of the prostate cancer) [38], besides the production of fine chemicals including chlorobenzene [39], toluene diisocyanates [40], aniline and toluenediamine [41].…”
Section: Introductionmentioning
confidence: 99%
“…High shear mixer (HSM), which has been widely utilized in fine dispersions and uniform reactive mixing process due to their highly mass and heat transfer speeds than conventional mechanically impellers [32][33][34][35][36]. Recently, HSM has been adopted to control the crystal polymorph of apixaban (an anticoagulant for the prevention of venous thromboembolism) [37] and BMS-A (a potential drug of the prostate cancer) [38], besides the production of fine chemicals including chlorobenzene [39], toluene diisocyanates [40], aniline and toluenediamine [41].…”
Section: Introductionmentioning
confidence: 99%
“…They are therefore used in a range of power intensive applications for break up (of agglomerates or droplets), fast chemical reactions or foam generation. Zhang et al (2012) provide a review of applications along with flow and power characteristics of different batch and in-line rotor stators relating to rotor-stators.…”
Section: Introductionmentioning
confidence: 99%
“…Although axial transport is reported in previous studies (Trivedi & Vasudeva, 1975), the theoretical analysis presented describes this phenomenon in a simplified manner as compared to the solution presented by Zhang et al 2012. The proposed model can be complemented for two liquids with different physical properties, to represent a more realistic additive injection problem, as presented in the oil industry or similar, but considering different physical properties, which is a matter of consideration for authors in further work.…”
Section: Experimental Observationsmentioning
confidence: 99%
“…Although computational fluid dynamics (CFD) methods have been implemented to study both, velocity and concentration profiles, it is interesting to provide analytical solutions (Zhang, Xu, & Li, 2012;Xue-Yi, Zhang, & Zheng, 2014) to describe phenomena such as flow in rotor-stator mixers (Barailler, Heniche & Tanguy, 2006. ), in helical coils (Trivedi & Vasudeva, 1975;Daskopoulos & Lenhoff, 1988), mixed convection in horizontal tubes (Chae & Chung, 2014) and free convection from horizontal cylinders (Chandra & Chhabra, 2012), all these under a laminar regime.…”
Section: Introductionmentioning
confidence: 99%