High-Speed Holography for In-Vivo Measurement of Acoustically Induced Motions of Mammalian Tympanic Membrane

Razavi, Payam; Cheng, Jeffrey; Furlong, Cosme; Rosowski, John J.

doi:10.1007/978-3-319-41351-8_11

Cited by 5 publications

(7 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Preliminary results on live animals show the applicability of the HDH as a quantitative full-field vibrometry tool to study TM mechanics in live ears for hearing research and the diagnosis of middle-ear disorders. 31 Previous models and measurements of the three-dimensional displacements of the TM support the approximation of the TM by a Kirchhoff-Love thin-shell in which the dominant motions occur along the direction normal to the TM surface. 22,[32][33][34][35] To accurately quantify the surface-normal displacements of the TM using a one-dimensional (1-D) HDH displacement measurement system (i.e., 1-D displacement sensitivity vector using single illumination and observation vector), knowledge of the TM shape and orientation are required.…”

Section: Introductionmentioning

confidence: 93%

“…We have previously developed and implemented HDH methods based on correlation interferometry that could "instantaneously" measure the full-field-of-view (>200;000 points at 67,200 camera frame rate) transient displacements of the TM in response to impulsive acoustical and mechanical excitations. 17,26,31 This…”

Section: Improved High-speed Digital Holographicmentioning

confidence: 99%

“…With the sensitivity map, the acoustically induced TM transient surface-normal displacements are determined from the interference phase measured by the 2 þ N HCI method. 31 The still images of Fig. 14(a) show the shape and surface-normal displacements at nine selected temporal instants from 1700 consecutive measurements (over 25 ms, @ 67200 FPS) during the TM transient response to a broadband acoustic click.…”

Section: Shape and Acoustically Induced Transient Surfacenormal Displmentioning

confidence: 99%

“…To solve this problem, high-speed digital holographic (HDH) methods were developed to measure the TM motions produced by brief acoustic transients (click response with duration of <5 ms). 17,26,29,30 The TM's responses to such brief broadband excitations (0.2 to 22 kHz) are rapid enough that they are little affected by slow in vivo physiological motions (<20 Hz), 17,26,30,31 and recording at high sampling rates (>40 kHz) provides broadband information about the TM's responses. Preliminary results on live animals show the applicability of the HDH as a quantitative full-field vibrometry tool to study TM mechanics in live ears for hearing research and the diagnosis of middle-ear disorders.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Combined high-speed holographic shape and full-field displacement measurements of tympanic membrane

et al. 2018

Self Cite

View full text Add to dashboard Cite

The conical shape of the tympanic membrane (TM or eardrum) plays an important role in its function, such that variations in shape alter the acoustically induced motions of the TM. We present a method that precisely determines both shape and acoustically induced transient response of the entire TM using the same optics and maintaining the same coordinate system, where the TM transient displacements due to a broadband acoustic click excitation (50-μs impulse) and the shape are consecutively measured within <200 ms. Interferograms gathered with continuous high-speed (>2 kHz) optical phase sampling during a single 100-ms wavelength tuning ramp allow precise and rapid reconstructions of the TM shape at varied resolutions (50 to 200 μm). This rapid acquisition of full-field displacements and shape is immune to slow disturbances introduced by breathing or heartbeat of live subjects. Knowledge of TM shape and displacements enables the estimation of surface normal displacements regardless of the orientation of the TM within the measurement system. The proposed method helps better define TM mechanics and provides TM structure and function information useful for the diagnosis of ear disease.

show abstract

Section: Introductionmentioning

confidence: 93%

Section: Improved High-speed Digital Holographicmentioning

confidence: 99%

Section: Shape and Acoustically Induced Transient Surfacenormal Displmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Combined high-speed holographic shape and full-field displacement measurements of tympanic membrane

et al. 2018

Self Cite

View full text Add to dashboard Cite

show abstract

“…and high sensitivity of the optical tools. Researchers utilized a high-speed digital holographic method to minimize these undesirable effects and made quantitative measurements on live subjects possible [24,[27][28][29][30].…”

Section: Introductionmentioning

confidence: 99%

High-Speed Holographic Shape and Full-Field Displacement Measurements of the Tympanic Membrane in Normal and Experimentally Simulated Pathological Ears

et al. 2019

Self Cite

View full text Add to dashboard Cite

To improve the understanding of the middle-ear hearing mechanism and assist in the diagnosis of middle-ear diseases, we are developing a high-speed digital holographic (HDH) system to measure the shape and acoustically-induced transient displacements of the tympanic membrane (TM). In this paper, we performed measurements on cadaveric human ears with simulated common middle-ear pathologies. The frequency response function (FRF) of the normalized displacement by the stimulus (sound pressure) at each measured pixel point of the entire TM surface was calculated and the complex modal indicator function (CMIF) of the middle-ear system based on FRFs of the entire TM surface motions was used to differentiate different middle-ear pathologies. We also observed changes in the TM shape and the surface motion pattern before and after various middle-ear manipulations. The observations of distinguishable TM shapes and motion patterns in both time and frequency domains between normal and experimentally simulated pathological ears support the development of a quantitative clinical holography-based apparatus for diagnosing middle-ear pathologies.

show abstract

Comparative Modal Analysis of the Tympanic Membrane Mechanics Between Normal and Experimentally Simulated Pathological Ears

Tang

Razavi

Maftoon

et al. 2019

Mechanics of Biological Systems and Materials &Amp; Micro-and Nanomechanics, Volume 4

View full text Add to dashboard Cite

High-Speed Holography for In-Vivo Measurement of Acoustically Induced Motions of Mammalian Tympanic Membrane

Cited by 5 publications

References 13 publications

Combined high-speed holographic shape and full-field displacement measurements of tympanic membrane

Combined high-speed holographic shape and full-field displacement measurements of tympanic membrane

High-Speed Holographic Shape and Full-Field Displacement Measurements of the Tympanic Membrane in Normal and Experimentally Simulated Pathological Ears

Comparative Modal Analysis of the Tympanic Membrane Mechanics Between Normal and Experimentally Simulated Pathological Ears

Contact Info

Product

Resources

About