High strength re-mineralizing, antibacterial dental composites with reactive calcium phosphates

Mehdawi, Idris Mohamed; Pratten, Jonathan; Spratt, David A.; Knowles, Jonathan C.; Young, Alison

doi:10.1016/j.dental.2013.01.010

Cited by 49 publications

(56 citation statements)

References 32 publications

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“…Although in recent years, attempts have been made to increase mechanical properties of chlorhexidine incorporated dental materials. Physical properties improved with the addition of silica/silicon carbide nanoparticles [154].…”

Section: Chlorhexidinementioning

confidence: 99%

Antimicrobial properties of conventional restorative filling materials and advances in antimicrobial properties of composite resins and glass ionomer cements—A literature review

2015

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Section: Chlorhexidinementioning

confidence: 99%

Antimicrobial properties of conventional restorative filling materials and advances in antimicrobial properties of composite resins and glass ionomer cements—A literature review

2015

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“…Composites have good esthetics, adhesion, and requires minimal cavity preparation. But on the other hand they are technically more difficult to place, and have higher failure rates due primarily to secondary caries beneath the restoration [3,4,5]. …”

Section: Introductionmentioning

confidence: 99%

Characterization of Dentine to Assess Bond Strength of Dental Composites

et al. 2015

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This study was performed to develop alternating dentine adhesion models that could help in the evaluation of a self-bonding dental composite. For this purpose dentine from human and ivory was characterized chemically and microscopically before and after acid etching using Raman and SEM. Mechanical properties of dentine were determined using 3 point bend test. Composite bonding to dentine, with and without use of acid pre-treatment and/or the adhesive, were assessed using a shear bond test. Furthermore, micro gap formation after restoration of 3 mm diameter cavities in dentine was assessed by SEM. Initial hydroxyapatite level in ivory was half that in human dentine. Surface hydroxyapatites decreased by approximately half with every 23 s of acid etch. The human dentine strength (56 MPa) was approximately double that of ivory, while the modulus was almost comparable to that of ivory. With adhesive use, average shear bond strengths were 30 and 26 MPa with and without acid etching. With no adhesive, average bond strength was 6 MPa for conventional composites. This, however, increased to 14 MPa with a commercial flowable “self–bonding” composite or upon addition of low levels of an acidic monomer to the experimental composite. The acidic monomer additionally reduced micro-gap formation with the experimental composite. Improved bonding and mechanical properties should reduce composite failures due to recurrent caries or fracture respectively.

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“…Partial replacement of calcium and phosphate with reinforcing opaque fillers improved the strength but these again compromised the mineral ion release and optical properties. 182 A recent study has introduced light-cured composites containing both MCPM and TCP with strength within the range expected for commercial composites. 183,184 HA precipitation at the surfaces of these composites was used to evaluate the remineralization potential of these materials.…”

Section: Composites Containing Ttcpsmentioning

confidence: 99%

“…[182][183][184][185] Highly soluble MCPM on the surface of the composite dissolved but at the core it reacted with β-TCP to form less soluble brushite (DCP dihydrate). Partial replacement of calcium and phosphate with reinforcing opaque fillers improved the strength but these again compromised the mineral ion release and optical properties.…”

Section: Composites Containing Ttcpsmentioning

confidence: 99%

Demineralization–remineralization dynamics in teeth and bone

Neel¹,

Aljabo²,

Strange³

et al. 2016

IJN

522

232

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Biomineralization is a dynamic, complex, lifelong process by which living organisms control precipitations of inorganic nanocrystals within organic matrices to form unique hybrid biological tissues, for example, enamel, dentin, cementum, and bone. Understanding the process of mineral deposition is important for the development of treatments for mineralization-related diseases and also for the innovation and development of scaffolds. This review provides a thorough overview of the up-to-date information on the theories describing the possible mechanisms and the factors implicated as agonists and antagonists of mineralization. Then, the role of calcium and phosphate ions in the maintenance of teeth and bone health is described. Throughout the life, teeth and bone are at risk of demineralization, with particular emphasis on teeth, due to their anatomical arrangement and location. Teeth are exposed to food, drink, and the microbiota of the mouth; therefore, they have developed a high resistance to localized demineralization that is unmatched by bone. The mechanisms by which demineralization–remineralization process occurs in both teeth and bone and the new therapies/technologies that reverse demineralization or boost remineralization are also scrupulously discussed. Technologies discussed include composites with nano- and micron-sized inorganic minerals that can mimic mechanical properties of the tooth and bone in addition to promoting more natural repair of surrounding tissues. Turning these new technologies to products and practices would improve health care worldwide.

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High strength re-mineralizing, antibacterial dental composites with reactive calcium phosphates

Cited by 49 publications

References 32 publications

Antimicrobial properties of conventional restorative filling materials and advances in antimicrobial properties of composite resins and glass ionomer cements—A literature review

Antimicrobial properties of conventional restorative filling materials and advances in antimicrobial properties of composite resins and glass ionomer cements—A literature review

Characterization of Dentine to Assess Bond Strength of Dental Composites

Demineralization–remineralization dynamics in teeth and bone

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High strength re-mineralizing, antibacterial dental composites with reactive calcium phosphates

Cited by 49 publications

References 32 publications

Antimicrobial properties of conventional restorative filling materials and advances in antimicrobial properties of composite resins and glass ionomer cements—A literature review

Antimicrobial properties of conventional restorative filling materials and advances in antimicrobial properties of composite resins and glass ionomer cements—A literature review

Characterization of Dentine to Assess Bond Strength of Dental Composites

Demineralization&ndash;remineralization dynamics in teeth and bone

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Product

Resources

About

Demineralization–remineralization dynamics in teeth and bone