High Times, Low Sats: Diffuse Pulmonary Infiltrates Associated with Chronic Synthetic Cannabinoid Use

Alhadi, Sameir; Tiwari, Anupama; Vohra, Rais; Gerona, Roy; Acharya, Janak; Bilello, Kathryn L.

doi:10.1007/s13181-013-0288-9

Cited by 53 publications

(38 citation statements)

References 25 publications

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“…Although the pulmonary involvement upon admission imitated pulmonary-renal syndrome, this diagnosis was excluded through clinical and laboratory findings. The lung involvement with SC use is well described in literature (4). We also think that SC use caused the pulmonary findings in this patient.…”

Section: Discussionsupporting

confidence: 69%

A New Enemy of the Kidneys: Synthetic Cannabinoids

Alp¹,

Akdam²,

Örmeci³

et al. 2017

Turk Neph Dial Transpl

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Section: Discussionsupporting

confidence: 69%

A New Enemy of the Kidneys: Synthetic Cannabinoids

Alp¹,

Akdam²,

Örmeci³

et al. 2017

Turk Neph Dial Transpl

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“…The effects of SC in the lungs range from non-specific pulmonary infiltrates, pulmonary hemorrhage and acute respiratory failure likely due to allergic alveolitis [28]. Cannabinoids cause inflammatory responses in the airways and lung parenchyma leading to histopathological changes [28].…”

Section: Discussionmentioning

confidence: 99%

Pneumomediastinum: A Complication of Synthetic Cannabinoid K2 Use

et al. 2016

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The use of synthetic cannabinoid K2 (SCK2) continues to rise. Products are sold in different flavors and mixed with various herbal products resulting in innumerable presenting symptoms. Common presentations are psychomotor activity, dystonia, hypertension, tachydysrhythmia, rhabdomyolysis, and renal failure. We present a 21-year-old woman who was admitted for severe nausea associated with several bouts of vomiting and upper abdominal pain. She had used SCK2 for recreation prior to the onset of her symptoms and she has been using SCK2 regularly for about a year. Chest and abdomen roentgenogram revealed pneumomediastinum. Esophagogram ruled out esophageal injury. She was managed conservatively with resolution of pneumomediastinum. We hypothesize that hyperemesis secondary to SCK2 use can increase the alveolar pressure leading to barotrauma. Although pneumomediastinum is a benign and selflimiting condition, esophagogram should be performed to exclude esophageal perforation which is a potentially life-threatening condition. Awareness of this presentation is important in order to evaluate for complications of barotrauma.

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“…Cases with diffuse infiltrates, nodular formations, or icy glass appearance in the lungs due to the use of bonsai and similar synthetic cannabinoids have begun to appear in the medical literature [5]. SME with subcutaneous emphysema has also been reported [1].…”

Section: Case Presentationmentioning

confidence: 99%

“…Subcutaneous emphysema is often detected [1]. Generally, SME follows a benign course , but in the presence of predisposing factors, such as asthma, or if massive, it can lead to respiratory failure or may even be fatal [5]. It is frequently seen in young men [5,6].…”

Section: Case Presentationmentioning

confidence: 99%

“…SME can usually be treated conservatively, but may also result in acute respiratory failure and sudden death. Monitoring patients in an intensive care unit can reduce mortality and morbidity [5,6]. The pathological findings and pathophysiology of the disease have not yet been completely determined because of the low number of cases with reported autopsy findings.…”

Section: Case Presentationmentioning

confidence: 99%

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Spontaneous Mediastinal Emphysema Associated with the Use of Synthetic Cannabinoid (Bonsai)

Chouseın

Iliaz

Nizam

et al. 2016

Turk Toraks Dergisi

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Spontaneous Mediastinal Emphysema (SME), which is a rarely seen case is defined as the detection of free air in the mediastinum without any trauma. Although rare, some cases secondary to drug use have been reported. In this study, two SME cases that developed due to the use of a synthetic cannabinoid known as "bonzai", which has recently become widespread in Turkey, are presented. We would like to emphasize that SME should also be considered in the differential diagnosis of patients who present with the symptoms of chest pain and dyspnea and have a history of drug use.

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High Times, Low Sats: Diffuse Pulmonary Infiltrates Associated with Chronic Synthetic Cannabinoid Use

Cited by 53 publications

References 25 publications

A New Enemy of the Kidneys: Synthetic Cannabinoids

A New Enemy of the Kidneys: Synthetic Cannabinoids

Pneumomediastinum: A Complication of Synthetic Cannabinoid K2 Use

Spontaneous Mediastinal Emphysema Associated with the Use of Synthetic Cannabinoid (Bonsai)

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