Higher Frequency of Thyroid Tumors in the Right Lobe

Abstract

Recently, using ultrasonography, we observed that the right lobe usually is larger compared with the left thyroid lobe. Since the higher cell number in a larger right lobe may confer a higher tumor risk, we investigated the location of benign and malignant lesions to test the hypothesis of a more frequent occurrence in this lobe. In 1,001 consecutive patients with benign thyroid lesions, tumors more frequently occurred in the right lobe (+21.5%, p = 0.0022). Furthermore, in 1,277 thyroid cancer patients with 1,302 thyroid cancers, the right lobe more often harbored the tumor initially (+22.9%, p = 0.0009). Our data show a larger proportion of both benign and malignant tumors in the right thyroid lobe.

Epidemiology, Clinic-histopathological features and Surgical treatment of Papillary Thyroid Cancer: A Retrospective Descriptive Study in Northwestern Algeria

“…In 41.8 percent of cases, malignant nodules were found in the right lobe, 40.8 percent in the left lobe, 5.8 percent in the bilateral lobe, and 3.9 percent in the isthmus, 2.9 percent in right Loboisthmic, while in 4.8 percent surgical specimen was not oriented. Several studies have indicated that the right lobe contains an increased number of cells that may contribute to a greater risk of tumor development (Gessl et al, 2010). Our findings were in contrast to that of (Bendouida et al, 2016), in which the majority of patients had malignant nodules located in the left lobe.…”

Is left-sided involvement of hepatocellular carcinoma an important preoperative predictive factor of poor outcome?

“…Renal cell carcinoma (RCC) located on the left with tumor thrombus does not have a worse prognosis than RCC located on the right [3]. In the thyroid, Gessl et al showed that a larger proportion of both benign and malignant tumors tended to affect the right lobe [4]. However, no study has attempted to investigate differences in features between the right and left hepatic lobes.…”