This paper deals with the boundary control problem of the unforced generalized Burgers-Huxley equation with high order nonlinearity when the spatial domain is [0, 1]. We show that this type of equations are globally exponential stable in L 2 [0, 1] under zero Dirichlet boundary conditions. We use an adaptive nonlinear boundary controller to show the convergence of the solution to the trivial solution and to show that it achieves global asymptotic stability in time. We introduce numerical simulation for the controlled equation using the Adomian decomposition method (ADM) in order to illustrate the performance of the controller.