Highly chemoselective turn-on fluorescent probe for ferrous (Fe2+) ion detection in cosmetics and live cells

Aggregation-induced emission (AIE) from poly(1,4-dihydropyridine)s synthesized by Hantzsch polymerization and their specific detection of Fe2+ ions

“…46 The World Health Organization (WTO) recommends that the Fe 2+ ion level in drinking water should be below 5.36 μM. 47 A rhodamine-based fluorescent probe was designed by Hou et al , and its Fe 2+ detection limit is 2–24 μM. 48 Therefore, it can be seen that PDPE-TO is a new sensitive probe that can sufficiently detect Fe 2+ ions in the fields of environmental and organism protection.…”

Recent Progress in Fluorescent Probes For Metal Ion Detection

“…Gao et al ( Gao et al, 2020 ) constructed a practical and novel Fe 2+ fluorescent probe via a unique strategy with Fe 2+ -induced reducing reaction, which can act in different monitoring of the environment, such as living cells. Khatun et al ( Khatun et al, 2020 ) developed a kind of “Turn-On” probe P-Fe (II), which is used to measure the exact amount of ferrous ion (Fe 2+ ) in cosmetics or living cells ( Figure 4B ). Liang et al ( Liang et al, 2021 ) developed a new camphor-based fluorimetic probe (CBO) with a natural monoterpene ketone camphor as a base material for the detection of Fe 2+ and it can be easily observed by fluorescence of Fe 2+ ions in some animals and in plant cells Fe 2+ imaging ( Figure 4C ).…”

“… (A) One-pot hydrothermal synthesis of fluorescent CDs as a highly efficient “on-off” fluorescent probe for the rapid detection of intracellular Fe 2+ ( Zhang X. et al, 2020 ); (B) The synthesis route of probe FeP1 ( Khatun et al, 2020 ); (C) The synthesis route of probe CBO ( Liang et al, 2021 ). …”

Luminescent Metal Complexes as Emerging Tools for Lipid Imaging

“…The analogous dinuclear complex 41 showed two-photon excitation and was used as CO sensor in vitro and in vivo; however, no investigation on the interaction of this probe with lipids has been reported [122,123]. A carbon monoxide-releasing Fischer carbene chromium complex (42) has been applied to HeLa cells, and co-localisation was observed with both Mitotracker Red and Nile Red [124]. This data suggests the probe localises non-specifically in both the mitochondria and LDs.…”

“…The literature contains an abundance of information on this topic, which is beyond the scope of this review. However, some prominent examples include "switch-on probes" that become luminescent upon coordination to Fe [40][41][42], Cu [43][44][45] or Zn [46,47], or "emission-shift probes" which exhibit a shift in emission upon coordination to Fe [48], Cu [49] or Zn [50][51][52][53]. There are several excellent reviews on luminescent metal probes for the interested reader [54][55][56][57].…”