Highly diastereoselective synthesis of benzothiazolo[3,2-a]pyridines via [4 + 2] annulation reaction of 2-vinylbenzothiazoles and azlactones

Abstract

An efficent AgOTf-catalyzed [4 + 2] annulation reaction of 2-vinylbenzothiazoles and azlactones was successfully described under mild reaction conditions. With this approach, a seires of novel benzothiazolo[3,2-a]pyridine derivatives was readily...