Highly Pathogenic Avian Influenza Virus A (H7N3) in Domestic Poultry, Saskatchewan, Canada, 2007

Berhane, Yohannes; Hisanaga, Tamiko; Kehler, Helen; Neufeld, James; Manning, Lisa; Argue, Connie K.; Handel, Katherine; Hooper-McGrevy, Kathleen; Jonas, Marilyn; Robinson, John H.; Webster, Robert G.; Pasick, John

doi:10.3201/eid1509.080231

Cited by 73 publications

(45 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Further studies indicated that a variety of charadriiform species are natural hosts of AIV [9,10,36 -38] and provide a reservoir for these viruses. [40]. AIV has been consistently isolated from birds (primarily from faecal samples) each year during the spring migration at Delaware Bay.…”

Section: Aiv and The Shorebirds Of Delaware Baymentioning

confidence: 97%

Coincident ruddy turnstone migration and horseshoe crab spawning creates an ecological ‘hot spot’ for influenza viruses

et al. 2010

Self Cite

View full text Add to dashboard Cite

Since 1985, avian influenza virus surveillance has been conducted annually from mid-May to early June in charadriiform species from the families Scolopacidae and Laridae (shorebirds and gulls) at Delaware Bay in the northeast United States. The mass migrations of shorebirds, gulls and horseshoe crabs (Limulus polyphemus) coincide at that time, and large numbers of migrating birds pause at Delaware Bay to feed on horseshoe crab eggs deposited at the high-tide line. Influenza viruses are consistently isolated from charadriiform birds at Delaware Bay, at an overall rate approximately 17 times the combined rate of isolation at all other surveillance sites worldwide (490 isolates/9474 samples, 5.2% versus 49 isolates per 15 848 samples, 0.3%, respectively; Proportion test, p , 0.0001). The likelihood of isolating influenza viruses at Delaware Bay is dependent on the presence of ruddy turnstone (Arenaria interpres) at the sampling site (G-test of independence, p , 0.001). The convergence of host factors and environmental factors results in a unique ecological 'hot spot' for influenza viruses in Charadriiformes.

show abstract

Section: Aiv and The Shorebirds Of Delaware Baymentioning

confidence: 97%

Coincident ruddy turnstone migration and horseshoe crab spawning creates an ecological ‘hot spot’ for influenza viruses

et al. 2010

Self Cite

View full text Add to dashboard Cite

show abstract

“…In May 2002, an outbreak at a broiler breeder farm in Chile was identified and later controlled by depopulation and strict biosecurity (12). Outbreaks of H7N3 HPAI in commercial poultry operations in British Columbia and Saskatchewan, Canada, in 2004 and 2007, respectively, were reported to be caused by LPAI virus precursors from migratory waterfowl (13)(14)(15).…”

mentioning

confidence: 99%

Characterization of the 2012 Highly Pathogenic Avian Influenza H7N3 Virus Isolated from Poultry in an Outbreak in Mexico: Pathobiology and Vaccine Protection

Kapczynski

Pantin‐Jackwood

Guzman

et al. 2013

J Virol

View full text Add to dashboard Cite

“…Unlike Eurasian HPAI H5N1 and H7N7 viruses which typically possess traditional multibasic amino acid HA cleavage sites, these HPAI H7N3 viruses all appear to have arisen from LPAI precursor viruses by nonhomologous recombination between the HA and other viral genes or host cell genetic sequences (Berhane et al 2009; Maurer-Stroh et al 2013; Pasick et al 2005; Suarez et al 2004). To date, H7 viruses are the only known subtype to use this mechanism as a way to acquire a virulent phenotype.…”

Section: North American Lineage Virusesmentioning

confidence: 99%

Mammalian Models for the Study of H7 Virus Pathogenesis and Transmission

Belser

Tumpey

2014

Influenza Pathogenesis and Control - Volume I

View full text Add to dashboard Cite

Mammalian models, most notably the mouse and ferret, have been instrumental in the assessment of avian influenza virus pathogenicity and transmissibility, and have been used widely to characterize the molecular determinants that confer H5N1 virulence in mammals. However, while H7 influenza viruses have typically been associated with conjunctivitis and/or mild respiratory disease in humans, severe disease and death is also possible, as underscored by the recent emergence of H7N9 viruses in China. Despite the public health need to understand the pandemic potential of this virus subtype, H7 virus pathogenesis and transmission has not been as extensively studied. In this review, we discuss the heterogeneity of H7 subtype viruses isolated from humans, and the characterization of mammalian models to study the virulence of H7 subtype viruses associated with human infection, including viruses of both high and low pathogenicity and following multiple inoculation routes. The use of the ferret transmission model to assess the influence of receptor binding preference among contemporary H7 influenza viruses is described. These models have enabled the study of preventative and therapeutic agents, including vaccines and antivirals, to reduce disease burden, and have permitted a greater appreciation that not all highly pathogenic influenza viruses are created equal.

show abstract

Highly Pathogenic Avian Influenza Virus A (H7N3) in Domestic Poultry, Saskatchewan, Canada, 2007

Cited by 73 publications

References 12 publications

Coincident ruddy turnstone migration and horseshoe crab spawning creates an ecological ‘hot spot’ for influenza viruses

Coincident ruddy turnstone migration and horseshoe crab spawning creates an ecological ‘hot spot’ for influenza viruses

Characterization of the 2012 Highly Pathogenic Avian Influenza H7N3 Virus Isolated from Poultry in an Outbreak in Mexico: Pathobiology and Vaccine Protection

Mammalian Models for the Study of H7 Virus Pathogenesis and Transmission

Contact Info

Product

Resources

About