2013
DOI: 10.1016/j.talanta.2012.10.079
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Highly selective colorimetric detection of spermine in biosamples on basis of the non-crosslinking aggregation of ssDNA-capped gold nanoparticles

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Cited by 27 publications
(16 citation statements)
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“…The hydrodynamic size increased with elevated SPM concentration, causing a larger degree of aggregation, but unlike the results from Liu et al. for 13 nm AuNPs, our results showed that the zeta‐potential of 4 nm AuNPs remained nearly constant instead of gradually restoring to a more positive level . This might be due to most SPM molecules being embedded in the core of aggregates.…”
Section: Resultscontrasting
confidence: 96%
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“…The hydrodynamic size increased with elevated SPM concentration, causing a larger degree of aggregation, but unlike the results from Liu et al. for 13 nm AuNPs, our results showed that the zeta‐potential of 4 nm AuNPs remained nearly constant instead of gradually restoring to a more positive level . This might be due to most SPM molecules being embedded in the core of aggregates.…”
Section: Resultscontrasting
confidence: 96%
“…During the study of the DNA concentration effect, it was interesting to observe a drop of sensitivity towards SPM when more DNA was added during the assay. This contradicted the previous suggestion that SPM‐induced aggregation occurred through DNA molecules by an ion‐bridging effect and non‐crosslinking mechanism . A control experiment in the absence of DNA was therefore performed to gain more information.…”
Section: Resultsmentioning
confidence: 67%
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“…Noble metal nanomaterials (e.g., Au and Ag) have been commonly used to develop highly sensitive colorimetric probes for the determination of biomolecules 21,22 , drugs 23 , toxicants [24][25][26][27][28] and small molecules [29][30][31] due to their optical and electrical properties and biocompatibility 32,33 . Ag nano materials are more cost effective in their preparation than Au nano materials.…”
Section: Introductionmentioning
confidence: 99%
“…Adsorption of ssDNA on Au NPs is well known for enhancing the electrostatic repulsion between Au NPs and preventing them from salt-induced aggregation. 26,27 Hence, we incubated CA aptamer sequences with Au NPs, and then challenged the Au NPs and Apt-Au NP solution with NaCl (25 mM and 50 mM). As shown in Fig.…”
Section: Resultsmentioning
confidence: 99%