Highly selectively monitoring heavy and transition metal ions by a fluorescent sensor based on dipeptide

A novel fluorescent chemosensor based on tetra-peptides for detecting zinc ions in aqueous solutions and live cells

“…[22][23][24][25][26][27][28][29] Compared with the traditional ways, [30][31][32][33][34][35] peptide-based fluorescent chemosensors have their own modular nature, i.e. [36][37][38][39][40][41][42][43] Taking these advantages, developing peptide-based fluorescent sensors using cell imaging becomes a hot research topic in chemical biology. [36][37][38][39][40][41][42][43] Taking these advantages, developing peptide-based fluorescent sensors using cell imaging becomes a hot research topic in chemical biology.…”

Metalloproteinek fémkötőhelyein alapuló oligopeptidek, mint potenciális toxikus fémion érzékelők

“…3 Számos publikáció igazolja a fenti szerkezeti csoportokba sorolható fluorofór-jelzett peptidek alkalmazhatóságát fémionok érzékelésére. Mûködési elvük szerint "TURN ON" választ adó CHEF (chelation-enhanced fluorescence), [14][15][16][17] "TURN OFF" jellegû CHEQ (chelation-enhanced quenching), 17,18 illetve FRET típusú szenzorokat is vizsgáltak. 19,20 A szenzorikai alkalmazhatóság szempontjából ideális "TURN ON" választ, de a "TURN OFF" effektust is a fluorofór gerjesztett állapotának HOMO 21 Mindenképpen meg kell jegyezni, hogy CHEF vagy CHEQ hatást más mechanizmusok is eredményezhetnek.…”

Highly selective colorimetric and fluorescent detection for Hg2+ in aqueous solutions using a dipeptide-based chemosensor

“…In recent years, fluorescent chemosensors for HTM based on amino acids or peptides have received many attentions because they dissolved well in aqueous solutions and exhibited selective and sensitive fluorescent responses to specific metal ions. [21][22][23][24][25][26][27][28][29][30][31][32] On the other hand, it is very rare to developing colorimetric chemosensors based on peptides for monitoring HTM. In the present study, we synthesized a new colorimetric chemosensor based on a dipeptide containing a disulfide bond as following reasons.…”