Highly Sensitive and High-Throughput Magnetic Resonance Thermometry of Fluids Using Superparamagnetic Nanoparticles

Chalise, Darshan; Cahill, David G.

doi:10.1103/physrevapplied.19.014055

Cited by 6 publications

(2 citation statements)

References 34 publications

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“…The domain-wall energy is responsible for the larger interfacial area between domains, and the magnetostatic energy grows proportionately with the volume of the material [ 43 ]. The energy required to create domain barriers is substantially more than the magnetostatic energy required to maintain a single-domain NP; hence, there is a critical value below which a stable single-domain NP can be established when the size of ferromagnetic materials is lowered to the nanoscale level [ 44 ]. As illustrated in Figure 2 , the critical size ( r c ) of an NP may be stated according to Equation (1) when the magnetostatic energy is equal to the domain-wall energy and the NP is transitioning from the multidomain state to the single-domain state [ 45 ].…”

Section: Types Of Magnetic and Fluorescent Nanoparticlesmentioning

confidence: 99%

Bioimaging Probes Based on Magneto-Fluorescent Nanoparticles

Ganguly

Margel

2023

Pharmaceutics

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Novel nanomaterials are of interest in biology, medicine, and imaging applications. Multimodal fluorescent-magnetic nanoparticles demand special attention because they have the potential to be employed as diagnostic and medication-delivery tools, which, in turn, might make it easier to diagnose and treat cancer, as well as a wide variety of other disorders. The most recent advancements in the development of magneto-fluorescent nanocomposites and their applications in the biomedical field are the primary focus of this review. We describe the most current developments in synthetic methodologies and methods for the fabrication of magneto-fluorescent nanocomposites. The primary applications of multimodal magneto-fluorescent nanoparticles in biomedicine, including biological imaging, cancer treatment, and drug administration, are covered in this article, and an overview of the future possibilities for these technologies is provided.

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Section: Types Of Magnetic and Fluorescent Nanoparticlesmentioning

confidence: 99%

Bioimaging Probes Based on Magneto-Fluorescent Nanoparticles

Ganguly

Margel

2023

Pharmaceutics

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“…The use of hyperthermia in cancer therapy has expanded significantly. These MNPs used in biological applications should be super paramagnetic at room temperature [20][21][22]. CIONPs have received much interest and attention from many researchers because of the slow magnetic moment relaxation of CoFe 2 O 4 compared to Fe 3 O 4 nanoparticles.…”

Section: Introductionmentioning

confidence: 99%

Cobalt Iron Oxide (CoFe2O4) Nanoparticles Induced Toxicity in Rabbits

Khan

Buzdar

Hussain

et al. 2023

Veterinary Sciences

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The market for nanoparticles has grown significantly over the past few decades due to a number of unique qualities, including antibacterial capabilities. It is still unclear how nanoparticle toxicity works. In order to ascertain the toxicity of synthetic cobalt iron oxide (CoFe2O4) nanoparticles (CIONPs) in rabbits, this study was carried out. Sixteen rabbits in total were purchased from the neighborhood market and divided into two groups (A and B), each of which contained eight rabbits. The CIONPs were synthesized by the co-precipitation method. Crystallinity and phase identification were confirmed by X-ray diffraction (XRD). The average size of the nanoparticles (13.2 nm) was calculated by Scherrer formula (Dhkl = 0.9 λ/β cos θ) and confirmed by TEM images. The saturation magnetization, 50.1 emug−1, was measured by vibrating sample magnetometer (VSM). CIONPs were investigated as contrast agents (CA) for magnetic resonance images (MRI). The relaxivity (r = 1/T) of the MRI was also investigated at a field strength of 0.35 T (Tesla), and the ratio r2/r1 for the CIONPs contrast agent was 6.63. The CIONPs were administrated intravenously into the rabbits through the ear vein. Blood was collected at days 5 and 10 post-exposure for hematological and serum biochemistry analyses. The intensities of the signal experienced by CA with CIONPs were 1427 for the liver and 1702 for the spleen. The treated group showed significantly lower hematological parameters, but significantly higher total white blood cell counts and neutrophils. The results of the serum biochemistry analyses showed significantly higher and lower quantities of different serum biochemical parameters in the treated rabbits at day 10 of the trial. At the microscopic level, different histological ailments were observed in the visceral organs of treated rabbits, including the liver, kidneys, spleen, heart, and brain. In conclusion, the results revealed that cobalt iron oxide (CoFe2O4) nanoparticles induced toxicity via alterations in multiple tissues of rabbits.

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