Highly sensitive electrodic materials based on Pt nanoflowers grown on Pt nanospheres for biosensor development

Abstract

Abstract-In this work we describe the realization of monometallic nanostructures by two simple electrodeposition steps. The surface of the modified electrode was characterized by scanning electron microscopy that confirms a homogeneous deposition of Pt nanospheres decorated with Pt nanoflowers. The so obtained nanostructured sensor exhibited good amperometric response towards hydrogen peroxide sensing at +0.30 V vs Ag|AgCl|Cl -. Therefore, it is especially useful toward glucose detection with reduced interferences. Glucose oxidase was immobilized onto the nanostructured surface by cross-linking with glutaraldehyde and the biosensor was characterized by chronoamperometric method in phosphate buffer. The biosensor showed a sensitivity of 29 ± 2 μA/(mM cm 2 ). Measurements in cell media reveal that the Pt-Pt hybrid nanostructures are promising for real-time glucose monitoring in real biosample.

Cholesterol biosensing with a polydopamine-modified nanostructured platinum electrode prepared by oblique angle physical vacuum deposition

“…S5ain the supporting information) showed a clear enhancement in sensitivity at +0.2 V, a maximum at +0.4 V and no additional improvement at higher potentials. This behavior, agreeing with both the CV data discussed above and the good electrocatalytic activity of nanostructured Pt electrodes previously reported by other authors[61,62], strongly supports the use of these electrodes as a robust device for the detection of cholesterol.…”

“…Traditionally, in most biosensors based on Pt electrodes, detection of H 2 O 2 is carried out at relatively high potentials (ca. +0.7 V),conditions that are prompt to interferences with other electroactive stuffs in the medium[4,61]. Evaluation of the Au-SPE/Pt-ChOx biosensor in the range 0 to +0.7 V (seeFig.…”