Highly sensitive gold nanoparticles-based optical sensing of DNA hybridization using bis(8-hydroxyquinoline-5-solphonate)cerium(III) chloride as a novel fluorescence probe

Shamsipur, Mojtaba; Memari, Zahra; Norouzi, Parviz; Faridbod, Farnoush

doi:10.1016/j.jpba.2015.10.046

Cited by 21 publications

(8 citation statements)

References 28 publications

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“…Moreover, the modification of the electronic layer at the GNP surface by the use of different ligands, a larger surface or a change of the medium's dielectric constant, leads to the modulation of the GNP plasmon band. This plasmon band allows the use of GNP for labeling, imaging, optical and electrochemical recognition, and diagnosis and therapy . Furthermore, most of cytotoxicity studies report low or no toxicity due to the inert nature of gold and the biocompatibility of the chosen ligands .…”

Section: Introductionmentioning

confidence: 99%

Gold nanoparticles in ophthalmology

Masse

Ouellette

Lamoureux

et al. 2018

Medicinal Research Reviews

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Many research projects are underway to improve the diagnosis and therapy in ophthalmology. Indeed, visual acuity deficits affect 285 million people worldwide and different strategies are being developed to strengthen patient care. One of these strategies is the use of gold nanoparticles (GNP) for their multiple properties and their ability to be used as both diagnosis and therapy tools. This review exhaustively details research developing GNPs for use in ophthalmology. The toxicity of GNPs and their distribution in the eye are described through in vitro and in vivo studies. All publications addressing the pharmacokinetics of GNPs administered in the eye are extensively reviewed. In addition, their use as biosensors or for imaging with optical coherence tomography is illustrated. The future of GNPs for ophthalmic therapy is also discussed. GNPs can be used to deliver genes or drugs through different administration routes. Their antiangiogenic and anti-inflammatory properties are of great interest for different ocular pathologies. Finally, GNPs can be used to improve stereotactic radiosurgery, brachytherapy, and photothermal therapy because of their many properties.

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Section: Introductionmentioning

confidence: 99%

Gold nanoparticles in ophthalmology

Masse

Ouellette

Lamoureux

et al. 2018

Medicinal Research Reviews

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“…The transfer efficiency between FRET pair depends on the orientation and distance between the FRET pair and the overlap of absorption spectra of the acceptor and the emission spectra of the donor [141]. Shamsipur et al [142] developed fluorescence biosensor based on the quenching ability of AuNPs for determination of DNA hybridization. Upon adding the complementary target DNA to the solution containing probe DNA-functionalized AuNPs and bis(8-hydroxyquinoline-5-solphonate) cerium(III) chloride as fluorescent probe, the quenching of the fluorophore agent was observed so that the quenching intensity was proportional to the concentration of the target DNA.…”

Section: The Functions Of Mnps In Various Biosensor Typesmentioning

confidence: 99%

Noble metal nanoparticles in biosensors: recent studies and applications

Malekzad

Zangabad

Mirshekari

et al. 2017

Nanotechnology Reviews

305

119

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The aim of this review is to cover advances in noble metal nanoparticle (MNP)-based biosensors and to outline the principles and main functions of MNPs in different classes of biosensors according to the transduction methods employed. The important biorecognition elements are enzymes, antibodies, aptamers, DNA sequences, and whole cells. The main readouts are electrochemical (amperometric and voltametric), optical (surface plasmon resonance, colorimetric, chemiluminescence, photoelectrochemical, etc.) and piezoelectric. MNPs have received attention for applications in biosensing due to their fascinating properties. These properties include a large surface area that enhances biorecognizers and receptor immobilization, good ability for reaction catalysis and electron transfer, and good biocompatibility. MNPs can be used alone and in combination with other classes of nanostructures. MNP-based sensors can lead to significant signal amplification, higher sensitivity, and great improvements in the detection and quantification of biomolecules and different ions. Some recent examples of biomolecular sensors using MNPs are given, and the effects of structure, shape, and other physical properties of noble MNPs and nanohybrids in biosensor performance are discussed.

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“…In order to eliminate electrical interference and the need for professional handling skills, an optical DNA biosensor is an alternative to the conventional molecular biology techniques and electrochemical methods [ 10 ]. Optical biosensors have attracted the attention of many researchers because of their small size, ease of operation and freedom from electrical induced noise [ 11 , 12 , 13 ]. The principle of optical sensing is typically based on the interaction between a sample and light.…”

Section: Introductionmentioning

confidence: 99%

Optical DNA Biosensor Based on Square-Planar Ethyl Piperidine Substituted Nickel(II) Salphen Complex for Dengue Virus Detection

Ariffin

Tan

Karim

et al. 2018

Sensors

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A sensitive and selective optical DNA biosensor was developed for dengue virus detection based on novel square-planar piperidine side chain-functionalized N,N′-bis-4-(hydroxysalicylidene)-phenylenediamine-nickel(II), which was able to intercalate via nucleobase stacking within DNA and be functionalized as an optical DNA hybridization marker. 3-Aminopropyltriethoxysilane (APTS)-modified porous silica nanospheres (PSiNs), was synthesized with a facile mini-emulsion method to act as a high capacity DNA carrier matrix. The Schiff base salphen complexes-labelled probe to target nucleic acid on the PSiNs renders a colour change of the DNA biosensor to a yellow background colour, which could be quantified via a reflectance transduction method. The reflectometric DNA biosensor demonstrated a wide linear response range to target DNA over the concentration range of 1.0 × 10−16–1.0 × 10−10 M (R2 = 0.9879) with an ultralow limit of detection (LOD) at 0.2 aM. The optical DNA biosensor response was stable and maintainable at 92.8% of its initial response for up to seven days of storage duration with a response time of 90 min. The reflectance DNA biosensor obtained promising recovery values of close to 100% for the detection of spiked synthetic dengue virus serotypes 2 (DENV-2) DNA concentration in non-invasive human samples, indicating the high accuracy of the proposed DNA analytical method for early diagnosis of all potential infectious diseases or pathological genotypes.

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Highly sensitive gold nanoparticles-based optical sensing of DNA hybridization using bis(8-hydroxyquinoline-5-solphonate)cerium(III) chloride as a novel fluorescence probe

Cited by 21 publications

References 28 publications

Gold nanoparticles in ophthalmology

Gold nanoparticles in ophthalmology

Noble metal nanoparticles in biosensors: recent studies and applications

Optical DNA Biosensor Based on Square-Planar Ethyl Piperidine Substituted Nickel(II) Salphen Complex for Dengue Virus Detection

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