Highly sensitive plasmonic biosensor for hepatitis B virus DNA based on the surface etching of the active helical gold nanorods

Recent progress on DNAzyme-based biosensors for pathogen detection

“…107 Cheng et al successfully detected hepatitis B virus (HBV) DNA using signal output by photo-etching. 108 They mainly catalyzed the generation of ˙OH from H 2 O 2 to etch the material, which resulted in a reduction in the scattering intensity of helical gold nanorods to achieve signal output.…”

Plasmonic biochips with enhanced stability in harsh environments for the sensitive detection of prostate-specific antigen

“…Plasmonic nanomaterials have been demonstrated for highly sensitive biosensing applications due to their distinctive localized surface plasmon resonance (LSPR) properties. 1–5 Yolk–shell plasmonic nanomaterials, which consist of solid nanomaterials as the core and nanocage as the shell, have been reported to exhibit excellent optical properties because of their high surface-to-volume ratio, interior vacancies, and high density of electromagnetic fields. 6,7 These unique optical properties render them exceedingly promising for chemical detection and medical diagnostics applications.…”

A near-infrared plasmonic biosensor for detection of morphine and codeine in biological samples based on the end-to-end assembly of modified gold nanorods

“…It was observed that a slight variation of the refractive index in the vicinity of the AuNRs will induce a significant change in LSPR as compared to the TSPR, making them potentially useful for sensing various kinds of targeted molecules in the environment. 27–30 Interestingly, AuNRs can be designed in either end-to-end linear chains or side-by-side motifs due to their anisotropic shape. 31,32 Indeed, the arrangements of AuNRs in the presence of adsorbates generate a new hybridized plasmon mode which typically results in a significant shift and a concomitant broadening of the SPR band suggesting a more sensitive assay down to nanomolar concentrations.…”