Highly sensitive trivalent copper chelate-luminol chemiluminescence system for capillary electrophoresis detection of epinephrine in the urine of smoker

Li, Tao; Wang, Zuorong; Xie, Haoyue; Fu, Zhifeng

doi:10.1016/j.jchromb.2012.10.017

Cited by 33 publications

(17 citation statements)

References 37 publications

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“…These methods consist of chemiluminescence [22], chromatographic methods [23], capillary electrophoresis [24], flow injection analysis [25] and spectroscopic methods [26]. However, these methods need more complicated procedures, costly instrumentation and over analysis time when compared to electroanalytical methods.…”

Section: Introductionmentioning

confidence: 99%

Electrocatalytic boost up of epinephrine and its simultaneous resolution in the presence of serotonin and folic acid at poly(serine)/multi-walled carbon nanotubes composite modified electrode: A voltammetric study

Narayana

Reddy

Gopal

et al. 2015

Materials Science and Engineering: C

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Section: Introductionmentioning

confidence: 99%

Electrocatalytic boost up of epinephrine and its simultaneous resolution in the presence of serotonin and folic acid at poly(serine)/multi-walled carbon nanotubes composite modified electrode: A voltammetric study

Narayana

Reddy

Gopal

et al. 2015

Materials Science and Engineering: C

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“…Bu nedenle, EP derişiminin farmasötik numuneler ile plazma ve idrar gibi çeşitli biyolojik sıvılarda belirlenmesi farmakolojik araştırmalar, sinir fizyolojisi ve yaşam bilimleri çalışmaları için önemlidir [8]. Literatürde bildirilen EP tayini çalışmalarında kullanılan analiz yöntemlerine yüksek performanslı sıvı kromatografisi (HPLC) [9,10], spektrofotometri [11][12][13], florimetri [14], kılcal elektroforez [15,16], kemilüminesans [17,18] ve elektrojenlenmiş kemilüminesans [19,20] örnek olarak verilebilir. Bununla birlikte, EP molekülleri kolay yükseltgenebildiği için, son yıllarda EP tayininin elektrokimyasal yöntemler kullanılarak gerçekleştirilmesi ile ilgili çalışmalara sıklıkla yer verilmektedir [21][22][23].…”

Section: Gi̇ri̇ş (Introduction)unclassified

Elektropolimerize 3,5-Diamino-1,2,4-Triazol Film ile Modifiye Edilmiş Altın Elektrot Yüzeyinde Epinefrinin Voltametrik Tayini ve Elektrokimyasal Davranışı

Calam

2019

Gazi Üniversitesi Fen Bilimleri Dergisi Part C: Tasarım Ve Teknoloji

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In this study, 3,5-diamino-1,2,4-triazole (35DT) was deposited on the gold electrode (Au) to fabricate a new sensor and used for the determination of ephinephrine (EP). Comparing with the bare Au and modified electrode (35DT-Au), the 35DT-Au modified electrode has higher catalytic activities towards the oxidation of EP. Figure A shows that electrode modification process. Figure A. CVs of 1mM 35DT on the bare Au electrode (10 cycle) Purpose: The aim of this study to develop a new and applicable modified electrode in real samples such as drugs used for the determination of EP. Theory and Methods: Epinephrine (EP) is found in biological body fluids. If strong emotions such as fear or anger are felt, EP is released into the bloodstream and causes an increase in heart rate, blood pressure and sugar. Many physiological events are associated with EP levels in body fluid. Therefore, determination of EP concentration in pharmaceutical samples and various biological fluids is important for pharmacological research. The electrochemical behavior of EP on the 35DT-Au surface was investigated using the DPV and CV techniques and optimum conditions was determined. Results: The accuracy and precision studies for EP determination in the drug sample were expressed in values of RSD% and bias%, respectively. The bias% values for the determination of drug samples containing 5 μM and 15 μM EP were 0.4% and-4.07%, respectively; BSS% values were calculated as 0.4% and 2.72%, respectively. Conclusion: In this study, a gold electrode modified with 3,5-diamino-1,2,4-triazole was used for EP determination. It is important to develop methods for the determination of EP, since the concentration of EP in the body fluid is lower or higher than the normal level, leading to various diseases. The modified electrode showed a wide linear working range compared to the modified electrodes prepared by alternative methods in the literature. Furthermore, the preparation of this sensor is simple and fast. The proposed sensor (35DT-Au) provided accuracy, selectivity, short measuring time, ease of preparation, good accuracy and good analytical performance. This modified electrode preparation process is a simple and fast process, does not require any pretreatment, and shows satisfactory stability and reproducibility, provides a good alternative to current studies in the literature. In addition, the EP electrode was successfully applied with the modified electrode.

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“…Examples are those involving high performance liquid chromatography (HPLC) [3,4], extraction prior of fluorometric detection [5], solid-phase extraction for liquid chromatography [6], solid-phase extraction combined with LC-MS/MS [7], chemiluminescence [8], solid phase reactor based on molecularly imprinted polymer (MIP) [9] and others. Usually these techniques result in low analytical frequencies requiring complex sample preparation and generation of relatively large amounts of waste.…”

Section: Introductionmentioning

confidence: 99%

Determination of Epinephrine at a Screen-Printed Composite Electrode Based on Graphite and Polyurethane

Iarb¹,

Tr²,

Cervini³

et al. 2017

J Anal Bioanal Tech

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Highly sensitive trivalent copper chelate-luminol chemiluminescence system for capillary electrophoresis detection of epinephrine in the urine of smoker

Cited by 33 publications

References 37 publications

Electrocatalytic boost up of epinephrine and its simultaneous resolution in the presence of serotonin and folic acid at poly(serine)/multi-walled carbon nanotubes composite modified electrode: A voltammetric study

Electrocatalytic boost up of epinephrine and its simultaneous resolution in the presence of serotonin and folic acid at poly(serine)/multi-walled carbon nanotubes composite modified electrode: A voltammetric study

Elektropolimerize 3,5-Diamino-1,2,4-Triazol Film ile Modifiye Edilmiş Altın Elektrot Yüzeyinde Epinefrinin Voltametrik Tayini ve Elektrokimyasal Davranışı

Determination of Epinephrine at a Screen-Printed Composite Electrode Based on Graphite and Polyurethane

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