Hiperaldosteronismo primario y embarazo: Lecciones obtenidas de 2 casos clínicos

A, Alfredo M Germain; G, Cristián Kottman; S, Gloria Valdés

doi:10.4067/s0034-98872002001200010

Cited by 3 publications

(2 citation statements)

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“…The excess aldosterone causes mineralocorticoid hypertension (14). There have been courses of normotensive pregnancies followed by postpartum hypertension, further diagnosed as PA (15). PA type 1 is a familial autosomal dominant disease that results from the fusion of genes encoding cortisol in response to ACTH and aldosterone in response to angiotensin.…”

Section: Primary Hyperaldosteronismmentioning

confidence: 99%

Cushing Syndrome in Pregnancy: A Case Presentation and Review of Literature

Samimagham

Ziaei

Tamaddondar

et al. 2023

J Kermanshah Univ Med Sci

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: The Cushing syndrome typically presents with abdominal obesity, wide purple striae, glucose intolerance, hypertension, easy bruising, and muscle weakness, a rare disorder interfering with ovulation, making the combination of Cushing syndrome and pregnancy less common. Nevertheless, Cushing syndrome has been reported in pregnancy. Here we report another case of pregnancy with Cushing syndrome, which presents merely with obesity, hypertension, and glucose intolerance, using a literature review at the end.

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Section: Primary Hyperaldosteronismmentioning

confidence: 99%

Cushing Syndrome in Pregnancy: A Case Presentation and Review of Literature

Samimagham

Ziaei

Tamaddondar

et al. 2023

J Kermanshah Univ Med Sci

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“…A diferencia de otras hipertensiones crónicas, que pueden mostrar mejoría de la PA durante el segundo trimestre, en el HAP el beneficio se prolonga hasta el tercer trimestre, e incluso hasta el postparto. El descenso se atribuye a la inhibición competitiva de aldosterona por la progesterona placentaria y a la estimulación de los sistemas vasodilatadores en el embarazo 25 . Sin embargo, hay casos de HAP asociados a embarazo en que se agrava la HTA 26 .…”

Section: Hta Secundariaunclassified

Hipertensión arterial en la mujer adulta

2013

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PROGRESS IN PRIMARY ALDOSTERONISM: Mineralocorticoid receptor antagonists and management of primary aldosteronism in pregnancy

Riester

Reincke

2015

European Journal of Endocrinology

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Primary aldosteronism (PA) is the most common cause of secondary hypertension. In this review, we discuss the diagnosis and management of PA during pregnancy based on the literature. As aldosterone and renin are physiologically increased during pregnancy and confirmation tests are not recommended, the diagnosis of PA during pregnancy relies on a repeatedly suppressed plasma renin level. Mineralocorticoid receptor antagonists (MRAs) are the most effective drugs to treat hypertension and hypokalemia in patients with PA. However, spironolactone (FDA pregnancy category C) might lead to undervirilization of male infants due to the anti-androgenic effects. Although data in the literature are very limited, treatment with spironolactone is not recommended. Eplerenone (FDA pregnancy category B) is a selective MRA without anti-androgenic potential. If MRA treatment is required in pregnancy, eplerenone appears to be a safe and effective alternative, although symptomatic treatment with approved antihypertensive drugs and supplementation with potassium is the first choice. In case of aldosterone-producing adenoma, laparoscopic adrenalectomy is a therapeutic option in the second trimester of pregnancy.

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Hiperaldosteronismo primario y embarazo: Lecciones obtenidas de 2 casos clínicos

Cited by 3 publications

References 0 publications

Cushing Syndrome in Pregnancy: A Case Presentation and Review of Literature

Cushing Syndrome in Pregnancy: A Case Presentation and Review of Literature

Hipertensión arterial en la mujer adulta

PROGRESS IN PRIMARY ALDOSTERONISM: Mineralocorticoid receptor antagonists and management of primary aldosteronism in pregnancy

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