Hiperplasia angiolinfóide com eosinofilia: relato de dois casos

Nogueira, Andreia; Filho, José Gomes Bezerra; Castro, Maria Cristina Ribeiro de; Maceira, Juan Piñeiro; Ramos‐e‐Silva, Márcia

doi:10.1590/s0365-05962003000100008

Cited by 8 publications

(8 citation statements)

References 10 publications

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“…There seems to be a higher incidence in females and lesions are more common in patients aged 20-50 years. 2 4. …”

Section: Discussionmentioning

confidence: 99%

“… 5 - 7 Some recent studies tend to consider it as a vascular malformation secondary to a subcutaneous arteriovenous shunt, but the hypothesis most widely accepted is that it is a reactive vascular hyperplasia to various stimuli. 1 , 4 …”

Section: Discussionmentioning

confidence: 99%

“…Because of their similarities, these two conditions were initially considered two outcomes of the same disease. 2 - 4 Although recent articles have established consistent differentiation criteria, there are still differences in the understanding of the two entities.…”

Section: Introductionmentioning

confidence: 99%

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Angiolymphoid hyperplasia with eosinophilia versus Kimura's disease: a case report and a clinical and histopathological comparison

Bastos¹,

Rocha²,

Silva³

et al. 2017

An. Bras. Dermatol.

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Angiolymphoid hyperplasia with eosinophilia is a rare and benign vascular tumor whose etiology remains uncertain. It clinically presents itself by angiomatous papules or nodules located on the head and neck. Many controversies in the literature are found in relation to angiolymphoid hyperplasia with eosinophilia and Kimura's disease - its main differential diagnosis - due to their clinical and histopathological similarities. However, currently, most studies agree that they are distinct diseases. The present case illustrates a characteristic description of angiolymphoid hyperplasia with eosinophilia and also highlights the main differences with Kimura's disease.

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“…There seems to be a higher incidence in females and lesions are more common in patients aged 20-50 years. 2 4. …”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Angiolymphoid hyperplasia with eosinophilia versus Kimura's disease: a case report and a clinical and histopathological comparison

Bastos¹,

Rocha²,

Silva³

et al. 2017

An. Bras. Dermatol.

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“…Contudo, há casos em que há recidiva e, nestes, alguns tratamentos propostos são: criocirurgia com nitrogênio líquido, radioterapia local ou injeções intralesionais de corticoide. 9,12,13,14 Existem casos relatados de regressão espontânea. 15 Há muita confusão na literatura médica para a distinção entre Hale e doença de Kimura.…”

Section: Discussionunclassified

Hiperplasia angiolinfoide como causa de eosinofilia

Bub¹,

Pereira²,

Oliveira³

et al. 2009

Rev. Bras. Hematol. Hemoter.

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IntroduçãoA hiperplasia angiolinfoide (Hale) foi inicialmente descrita em 1969, por Wells e Whimster, 1 e, na ocasião, foi denominada como hiperplasia angiolinfoide subcutânea com eosinofilia. A doença caracteriza-se por lesões papulosas ou nodulares, solitárias ou múltiplas, e de cor violácea, o que sugere a origem vascular da doença. As lesões estão frequentemente localizadas na fronte, face, região retroauricular e cervical. Parece haver maior incidência em indivíduos do sexo feminino, sendo mais comum em pacientes com idades entre 30 e 50 anos e sem predominância de raça. Sua etiopatogenia ainda permanece indefinida, contudo alguns trabalhos sugerem uma provável proliferação vascular anormal com resposta inflamatória secundária. 2A eosinofilia está presente em somente 20% dos casos Hale. O seu mecanismo fisiopatógico nesta patologia ainda é motivo de discussão, mas poderia ser explicado através da produção de interleucinas (principalmente interleucina -5 e 3) pelos linfócitos presentes nas lesões, com consequente ativação e diferenciação dos eosinófilos.

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“…[2][3][4][5] The treatment of ALHE, reserved for symptomatic and disfiguring cases, is considered a challenge, with multiple possible forms of management of varying success, ranging from topical treatments (tacrolimus, imiquimod), intralesional treatments (interferon, corticotherapy) and oral treatments (corticotherapy, retinoids). 4,6 Cases of spontaneous regression have been reported. Surgical excision is considered one of the most effective options; however, recurrence of the lesions occurs in around one-third of cases.…”

Section: Discussionmentioning

confidence: 99%

Caso para diagnóstico

Santiago

Reis²

2011

An. Bras. Dermatol.

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WHAT IS YOUR DIAGNOSIS? CASE REPORTA 22-year old male patient presented with skin lesions on his face that had been becoming progressively worse over the previous four years. The patient had no relevant personal history of atopy, infection or trauma associated with the appearance of the skin lesions. At objective examination, multiple erythematous, purplish, shiny, hard papules and nodules were found, some with superficial erosion and crusting. They were situated unilaterally on the right side of his face in the preauricular area, tragus and external auditory canal (Figures 1 and 2). The remainder of the objective examination was normal, with no adenopathies or locoregional masses being found. The lesions were asymptomatic, albeit sporadically friable.The skin biopsy showed a dense infiltrate in the dermis associated with capillary proliferation with hyperplasia of the endothelial cells, which were swollen and protruding towards the vascular lumen (Figure 3).Laboratory evaluation, which included full blood count with differential white blood cell count, serum biochemical tests, measurement of immunoglobulin levels and urinalysis, was normal.Various forms of treatment were implemented, albeit unsuccessfully: tacrolimus ointment, topical and oral corticotherapy and oral isotretinoin; however the best results were obtained with electrocoagulation and CO2 laser.

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Hiperplasia angiolinfóide com eosinofilia: relato de dois casos

Cited by 8 publications

References 10 publications

Angiolymphoid hyperplasia with eosinophilia versus Kimura's disease: a case report and a clinical and histopathological comparison

Angiolymphoid hyperplasia with eosinophilia versus Kimura's disease: a case report and a clinical and histopathological comparison

Hiperplasia angiolinfoide como causa de eosinofilia

Caso para diagnóstico

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