2011
DOI: 10.1590/s0365-05962011000500009
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Hiperplasia sebácea cutânea: estudo piloto para a correlação da doença com hormônios androgênios

Abstract: FUNDAMENTOS: As glândulas sebáceas são suscetíveis à ação dos hormônios androgênios e apresentam proliferação benigna com a idade, ou seja, hiperplasia. OBJETIVOS: Estudo piloto para verificar se há correlação entre a taxa de hormônios masculinos circulantes e o aumento da incidência da hiperplasia das glândulas sebáceas. MÉTODOS: 16 pacientes do sexo feminino, com diagnóstico de hiperplasia sebácea cutânea, foram comparados a um grupo-controle de mesmo gênero e idades semelhantes, sem a doença. Ambos os grupo… Show more

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Cited by 6 publications
(2 citation statements)
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“…The development and function of the sebaceous gland in the fetus and neonate are regulated by maternal androgen and the synthesis of endogenous steroids, which lead to increased sebaceous excretion within a few hours after birth. This fact can cause excessive proliferation and superficial visualization at the beginning of extrauterine life 22 . There was no statistical significance between sebaceous hyperplasia and maternal gestational intercurrences, which differs from other studies 11 .…”
Section: Discussioncontrasting
confidence: 57%
“…The development and function of the sebaceous gland in the fetus and neonate are regulated by maternal androgen and the synthesis of endogenous steroids, which lead to increased sebaceous excretion within a few hours after birth. This fact can cause excessive proliferation and superficial visualization at the beginning of extrauterine life 22 . There was no statistical significance between sebaceous hyperplasia and maternal gestational intercurrences, which differs from other studies 11 .…”
Section: Discussioncontrasting
confidence: 57%
“…These data collectively suggest that AR has an anti-proliferative function. Whether human SG hyperplasia is also linked to androgens is debated (Plewig and Kligman, 1978; Pochi et al., 1979; Tagliolatto et al., 2011). …”
Section: Resultsmentioning
confidence: 99%