Hippocampal Maturation in the Precocial Murid Rodent &lt;i&gt;Acomys cahirinu&lt;/i&gt;&lt;i&gt;s&lt;/i&gt;

Brunjes, Peter C.

doi:10.1159/000121305

Cited by 21 publications

(5 citation statements)

References 14 publications

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“…As a result, most DG neurons are born postnatally. In contrast, peak neurogenesis occurs prenatally in species with longer gestation periods, such as spiny mice, guinea pigs, and non-human primates, so that most DG neurons are instead generated prenatally ( Rakic and Nowakowski, 1981 ; Brunjes, 1984 ; Guidi et al, 2005 ). This shift in timing is further accentuated in humans where hippocampal neurogenesis begins in early gestation and peaks between the first and second trimester ( Yang et al, 2014 ; Cipriani et al, 2017 ; Sorrells et al, 2018 ).…”

Section: Progression Of Hippocampal Neurogenesis Is Conserved Between...mentioning

confidence: 99%

What Is the Relationship Between Hippocampal Neurogenesis Across Different Stages of the Lifespan?

Bond

Ming²,

Song³

2022

Front. Neurosci.

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Hippocampal neurogenesis has typically been studied during embryonic development or in adulthood, promoting the perception of two distinct phenomena. We propose a perspective that hippocampal neurogenesis in the mammalian brain is one continuous, lifelong developmental process. We summarize the common features of hippocampal neurogenesis that are maintained across the lifespan, as well as dynamic age-dependent properties. We highlight that while the progression of hippocampal neurogenesis across the lifespan is conserved between mammalian species, the timing of this progression is species-dependent. Finally, we discuss some current challenges in the hippocampus neurogenesis field, and future research directions to address them, such as time course analysis across the lifespan, mechanisms regulating neurogenesis progression, and interspecies comparisons. We hope that this new perspective of hippocampal neurogenesis will prompt fresh insight into previous research and inspire new directions to advance the field to identify biologically significant ways to harness the endogenous capacity for neurogenesis in the hippocampus.

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Section: Progression Of Hippocampal Neurogenesis Is Conserved Between...mentioning

confidence: 99%

What Is the Relationship Between Hippocampal Neurogenesis Across Different Stages of the Lifespan?

Bond

Ming²,

Song³

2022

Front. Neurosci.

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“…As a measure of goodness of fit, R 2 was calculated. Encephalization quotient (EQ) was calculated according to Boddy et al (2012): EQ = brain mass/(0.56 × body mass ∧ 0.746). Index of Neural Development (IND) was calculated as adapted from (Portmann, 1990) and (Grand, 1992): IND = developmental brain mass/adult brain mass.…”

Section: Image Acquisition and Analysismentioning

confidence: 99%

Developmental Differences in Neocortex Neurogenesis and Maturation Between the Altricial Dwarf Rabbit and Precocial Guinea Pig

et al. 2021

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Mammals are born on a precocial–altricial continuum. Altricial species produce helpless neonates with closed distant organs incapable of locomotion, whereas precocial species give birth to well-developed young that possess sophisticated sensory and locomotor capabilities. Previous studies suggest that distinct patterns of cortex development differ between precocial and altricial species. This study compares patterns of neocortex neurogenesis and maturation in the precocial guinea pig and altricial dwarf rabbit, both belonging to the taxon of Glires. We show that the principal order of neurodevelopmental events is preserved in the neocortex of both species. Moreover, we show that neurogenesis starts at a later postconceptional day and takes longer in absolute gestational days in the precocial than the altricial neocortex. Intriguingly, our data indicate that the dwarf rabbit neocortex contains a higher abundance of highly proliferative basal progenitors than the guinea pig, which might underlie its higher encephalization quotient, demonstrating that the amount of neuron production is determined by complex regulation of multiple factors. Furthermore, we show that the guinea pig neocortex exhibits a higher maturation status at birth, thus providing evidence for the notions that precocial species might have acquired the morphological machinery required to attain their high functional state at birth and that brain expansion in the precocial newborn is mainly due to prenatally initiating processes of gliogenesis and neuron differentiation instead of increased neurogenesis. Together, this study reveals important insights into the timing and cellular differences that regulate mammalian brain growth and maturation and provides a better understanding of the evolution of mammalian altriciality and presociality.

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“…Similar time courses have been described in mice, where granule cell generation starts at embryonic day 10, peaks at birth and tapers off at postnatal day 20 (Angevine, 1965). In precocial spiny mice that are born after a prolonged gestation period (38 day), the morphology of the dentate gyrus is already mature‐like at birth and slight volumetric growth can be observed only until postnatal day 10 (Brunjes, 1984). In the guinea pig, which is also precocial but has an even longer gestation (67 day) than spiny mice, neurogenesis is still prominent after birth but accounts for only ∼20% of the total granule cell number, and declines sharply after 3 weeks (Guidi et al.…”

Section: General Time‐dependent Features Of Granule Cell Genesis In Tmentioning

confidence: 99%

Comparing adult hippocampal neurogenesis in mammalian species and orders: influence of chronological age and life history stage

Amrein

Isler

Lipp

2011

Eur J of Neuroscience

165

161

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Adult hippocampal neurogenesis is a prominent event in rodents. In species with longer life expectancies, newly born cells in the adult dentate gyrus of the hippocampal formation are less abundant or can be completely absent. Several lines of evidence indicate that the regulatory mechanisms of adult neurogenesis differ between short- and long-lived mammals. After a critical appraisal of the factors and problems associated with comparing different species, we provide a quantitative comparison derived from seven laboratory strains of mice (BALB, C57BL/6, CD1, outbred) and rats (F344, Sprague-Dawley, Wistar), six other rodent species of which four are wild-derived (wood mouse, vole, spiny mouse and guinea pig), three non-human primate species (marmoset and two macaque species) and one carnivore (red fox). Normalizing the number of proliferating cells to total granule cell number, we observe an overall exponential decline in proliferation that is chronologically equal between species and orders and independent of early developmental processes and life span. Long- and short-lived mammals differ with regard to major life history stages; at the time points of weaning, age at first reproduction and average life expectancy, long-lived primates and foxes have significantly fewer proliferating cells than rodents. Although the database for neuronal differentiation is limited, we find indications that the extent of neuronal differentiation is subject to species-specific selective adaptations. We conclude that absolute age is the critical factor regulating cell genesis in the adult hippocampus of mammals. Ontogenetic and ecological factors primarily influence the regulation of neuronal differentiation rather than the rate of cell proliferation.

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Hippocampal Maturation in the Precocial Murid Rodent <i>Acomys cahirinu</i><i>s</i>

Cited by 21 publications

References 14 publications

What Is the Relationship Between Hippocampal Neurogenesis Across Different Stages of the Lifespan?

What Is the Relationship Between Hippocampal Neurogenesis Across Different Stages of the Lifespan?

Developmental Differences in Neocortex Neurogenesis and Maturation Between the Altricial Dwarf Rabbit and Precocial Guinea Pig

Comparing adult hippocampal neurogenesis in mammalian species and orders: influence of chronological age and life history stage

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