Hirschsprung’s Disease: A Regional Experience

Koh, Cherry; Yong, Tuck Leong; Fenton, Edmond

doi:10.1111/j.1445-2197.2008.04724.x

Cited by 7 publications

(4 citation statements)

References 17 publications

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“…Best et al showed a significant increase in incidence in North England between 1990 and 2008 ( p = 0.02), 8 and Koh et al also found a surge in cases in Tasmania between 2003 and 2005 for which no obvious explanation could be found. 5 Contrary to these studies, our results did not show any evidence of an increasing trend in the incidence of HD in Ontario between 1991 and 2013. Incidence estimates from Baltimore, 26 Japan, 7 Denmark, 6 and British Columbia 3 also did not show a change in HD diagnosis across time.…”

Section: Discussioncontrasting

confidence: 99%

“…The incidence rate of HD in Ontario (1 in 4,868 live births) is similar to that most often reported in North America and Europe (1 in 5,000 live births). 4 , 5 , 7 , 19 – 21 Our results are comparable to incidence rates described in British Columbia, 3 Southeast Scotland, 22 Denmark, 23 and the USA 24 , 25 ( Table 3 ). This is not surprising given the proposed association between race and incidence rates for HD.…”

Section: Discussionsupporting

confidence: 80%

“…Recent studies have also reported an increasing incidence of HD in the general population. 5 , 8 While this may be due to increased awareness of the disease and improved methods of detection, it must be noted that temporal trends have also been shown to vary by geographical region. 5 – 8 …”

Section: Introductionmentioning

confidence: 99%

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Validation of algorithms to determine incidence of Hirschsprung disease in Ontario, Canada: a population-based study using health administrative data

Nasr

Sullivan

Chan

et al. 2017

CLEP

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ObjectiveIncidence rates of Hirschsprung disease (HD) vary by geographical region, yet no recent population-based estimate exists for Canada. The objective of our study was to validate and use health administrative data from Ontario, Canada to describe trends in incidence of HD between 1991 and 2013.Study designTo identify children with HD we tested algorithms consisting of a combination of diagnostic, procedural, and intervention codes against the reference standard of abstracted clinical charts from a tertiary pediatric hospital. The algorithm with the highest positive predictive value (PPV) that could maintain high sensitivity was applied to health administrative data from April 31, 1991 to March 31, 2014 (fiscal years 1991–2013) to determine annual incidence. Temporal trends were evaluated using Poisson regression, controlling for sex as a covariate.ResultsThe selected algorithm was highly sensitive (93.5%) and specific (>99.9%) with excellent predictive abilities (PPV 89.6% and negative predictive value >99.9%). Using the algorithm, a total of 679 patients diagnosed with HD were identified in Ontario between 1991 and 2013. The overall incidence during this time was 2.05 per 10,000 live births (or 1 in 4,868 live births). The incidence did not change significantly over time (odds ratio 0.998, 95% confidence interval 0.983–1.013, p = 0.80).ConclusionOntario health administrative data can be used to accurately identify cases of HD and describe trends in incidence. There has not been a significant change in HD incidence over time in Ontario between 1991 and 2013.

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Section: Discussioncontrasting

confidence: 99%

Section: Discussionsupporting

confidence: 80%

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Validation of algorithms to determine incidence of Hirschsprung disease in Ontario, Canada: a population-based study using health administrative data

Nasr

Sullivan

Chan

et al. 2017

CLEP

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“…Dans notre étude, le genre masculin représentait 87,2 % (41cas). Ce qui concorde avec les études de Diaby [16], et Koh [17] dans respectivement 87% et 79,6% des cas.…”

Section: Discussionunclassified

Revue iconographique des différentes formes de la maladie de Hirschsprung au lavement opaque

Admin,

BADJINfally,

DEMEHamidou

et al. 2020

J Afr Imag Méd

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Methods : There is a cross-sectional study carried out over a period of 06 years, going from March 01, 2011 to February 28, 2017, important on 47 files of patients collected in the radiology departments of the Aristide Le Dantec Hospital and the Hospital of "Albert Children" Royer from Dakar-Senegal. We included any patient received for suspicion of Hirschsprung's disease, in whom the diagnosis was raised in barium development and who underwent surgery with the results of the anatomy of the operating room. Results : These were 41 boys and 06 girls, a gender ratio of 6.8. The average age was 39 months with extremes from 17 days to 10 years. Chronic constipation and delayed meconium emission accounted for 48.9% and 25.5% of the cases. The ASP showed 37 cases of diffuse aerocoly, 01 cases of hydroaeric level, 28 cases of sterco-aeric stasis, and 05 cases of lack of rectal ventilation. The opaque enema was in favor of Hirschsprung's disease in 47 patients. The aganglionic area was specified in 38 patients : recto-sigmoid 25 patients (65%), rectal 12 patients (32%) and 01 case (03%) with the descending colon. Ninety-seven percent of short and ultra short forms, 02.6% of extended forms and the recto sigmoid index (SRI) were specified in 11 patients. Thirty-eight cases confirmed on anatomical pathology examination with radio-anatomopathological concordance observed in 90.5% of cases. Conclusion : The opaque enema still retains its indications in Hirschsprung's disease. Knowledge of the different radiological forms makes it possible to make an early diagnosis of an optimal load price in the neonatal period. Résumé Objectifs : Illustrer les différentes formes de la maladie de Hirschsprung observées au cours du lavement opaque.Méthodes : Il s’agissait d’une étude transversale réalisée sur une période de 06ans, allant du 01 Mars 2011 au 28 Février 2017, portant sur 47 dossiers de patients colligés dans les services de radiologie de l’Hôpital Aristide Le Dantec et l’Hôpital d’Enfants Albert Royer de Dakar-Sénégal. Nous avons inclus tout patient reçu pour suspicion de la maladie de Hirschsprung, chez qui le diagnostic a été évoqué au lavement baryté et ayant bénéficié d’une intervention chirurgicale avec les résultats de l’examen d’anatomie pathologie de la pièce opératoire. Résultats : Il s’agissait de 41 garçons et de 06 filles soit un genre-ratio de 6,8. L’âge moyen était de 39 mois avec des extrêmes de 17 jours à 10 ans. La constipation chronique et le retard d’émission de méconium représentaient 48,9% et 25.5% des cas. L’ASP a montré 37cas d’aérocolie diffuse, 01cas de niveau hydroaérique, 28cas de stase sterco-aérique, et 05cas de défaut d’aération rectale. Le lavement opaque était en faveur de la maladie de Hirschsprung chez 47 patients. La zone aganglionnaire était précisée chez 38 patients : recto-sigmoïdienne 25patients (65%), rectale 12 patients (32%) et 01cas (03%) au colon descendant. Quatre-vingt-dix-sept pour cent de formes courtes et ultra courtes, 02,6% de formes étendues et l’index recto sigmoïdien (IRS) était précisé chez 11 patients. Trente-huit cas confirmés à l’examen d’anatomie pathologie avec une concordance radio-anatomopathologique observée dans 90,5% des cas.Conclusion : Le lavement opaque garde toujours ses indications dans de la maladie de Hirschsprung. La connaissance des différentes formes radiologiques permet de poser un diagnostic précoce gage d’une prise en charge optimale à la période néonatale

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Hirschsprung Disease

Heuckeroth¹

2012

Pediatric Neurogastroenterology

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Hirschsprung’s Disease: A Regional Experience

Abstract: The incidence of Hirschsprung's disease seems higher in Tasmania. The surge in the number of cases is also of interest, although the reasons behind this remain unknown. Delayed passage of meconium was also less common than previously cited.

Cited by 7 publications

References 17 publications

Validation of algorithms to determine incidence of Hirschsprung disease in Ontario, Canada: a population-based study using health administrative data

Validation of algorithms to determine incidence of Hirschsprung disease in Ontario, Canada: a population-based study using health administrative data

Revue iconographique des différentes formes de la maladie de Hirschsprung au lavement opaque

Hirschsprung Disease

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