Histiocytic Lymphadenopathy Secondary to Metallosis Following Hip Replacement

Cerilli, Lisa A.

doi:10.1177/1066896906292536

Cited by 3 publications

(2 citation statements)

References 2 publications

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“…Copious accumulation of metallic particulate debris and generation of foreign body granulomas can permeate beyond the joint capsule into the surrounding soft tissues. Pelvic lymph nodes draining these areas may also become involved by undergoing reactive histiocytic change [ 2 ]. Osteolysis of the periprosthetic osseous matter is also a common phenomenon that can occur as a result of severe metallosis [ 1 , 3 , 4 , 5 ].…”

Section: Discussionmentioning

confidence: 99%

Severe Periprosthetic Metallosis and Polyethylene Liner Failure Complicating Total Hip Replacement: The Cloud Sign

Paydar

Chew

Manner

2007

Radiology Case Reports

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We present a case of an 85-year-old woman with extensive metallosis of the left hip joint secondary to prosthetic polyethelene liner dislocation and wear. Radiographs demonstrated amorphous cloudy radiodensities surrounding the prosthesis, a feature we have called the “cloud sign.” The presence of amorphous cloudy radiodensities as a radiographic sign of metallosis has not been previously described to our knowledge.

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Section: Discussionmentioning

confidence: 99%

Severe Periprosthetic Metallosis and Polyethylene Liner Failure Complicating Total Hip Replacement: The Cloud Sign

Paydar

Chew

Manner

2007

Radiology Case Reports

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“…This large aggregate of particles can have local and systemic effects. In the case of metalon-metal prostheses, the local tissue reaction, quantified as per the number of histiocytes, is approximately one order of magnitude lower than in the case of metal-on-polyethylene prostheses [14]. Given the smaller size of metal particles compared to those derived from polyethylene, the number of histiocytes recruited to store the particles is lower [15].…”

Section: Discussionmentioning

confidence: 97%

N-Acetyl-Cysteine Reduces Blood Chromium and Cobalt Levels in Metal-on-Metal Hip Arthroplasty

D’Ambrosi

Ursino

2020

Arthroplasty Today

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The most common reasons for revision of metal-on-metal hip arthroplasty are aseptic loosening and metal reaction. Failure of a metal-on-metal implant due to the aggressive destruction of periprosthetic tissues may require extensive reconstruction procedures. The aim of this case report is to describe the treatment in an asymptomatic patient with high levels of chromium and cobalt, using chelation therapy. The rational use of N-acetyl-cysteine (NAC) involves thiol groups to chelate sites for metals. More than 10 years after the metal-on-metal hip arthroplasty, the patient did not have to undergo revision surgery; the levels of the ions in the blood were considerably lowered (chromium from 4.

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Delamination of Tantalum Porous Coating From a TKA Due to Regional Dissemination of Debris

Bonutti¹,

Pivec²,

Issa³

et al. 2013

Orthopedics

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Metallic debris from metal-on-metal bearings is a recognized mode of failure that may lead to implant loosening and periprosthetic soft tissue reactions. The sequelae of metallosis have been most commonly reported with respect to total hip arthroplasty. The authors report a rare case of metallosis following a hybrid metal-on-polyethylene total knee arthroplasty that used a porous tantalum tibial knee component. A total knee arthroplasty patient who presented with knee pain but normal radiographs was found to have delamination of her tibial component that resulted in marked periprosthetic soft tissue metallosis.

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Histiocytic Lymphadenopathy Secondary to Metallosis Following Hip Replacement

Cited by 3 publications

References 2 publications

Severe Periprosthetic Metallosis and Polyethylene Liner Failure Complicating Total Hip Replacement: The Cloud Sign

Severe Periprosthetic Metallosis and Polyethylene Liner Failure Complicating Total Hip Replacement: The Cloud Sign

N-Acetyl-Cysteine Reduces Blood Chromium and Cobalt Levels in Metal-on-Metal Hip Arthroplasty

Delamination of Tantalum Porous Coating From a TKA Due to Regional Dissemination of Debris

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