1924
DOI: 10.1001/archinte.1924.00110280081008
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Histologic Hydrogen-Ion Studies of the Kidney

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Cited by 13 publications
(6 citation statements)
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“…to a 9 kilo dog, and the kidneys were removed 12 minutes later instead of after half an hour, as in the experiment above. Microscopically the epithelium of the renal tubules appeared red although the urine secreted was yellow, a finding the opposite of that just described, but in agreement with the experiments of Stieglitz (7). The test was repeated on another 9 kilo animal with the same dosage of dye but one of the kidneys was removed half an hour after an alkaline reaction of the urine had been established, instead of after the lapse of but 12 minutes as in the previous experiment.…”
Section: Intravenous Injection Of 5 Per Cent Solution Of Sodium Bicarsupporting
confidence: 85%
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“…to a 9 kilo dog, and the kidneys were removed 12 minutes later instead of after half an hour, as in the experiment above. Microscopically the epithelium of the renal tubules appeared red although the urine secreted was yellow, a finding the opposite of that just described, but in agreement with the experiments of Stieglitz (7). The test was repeated on another 9 kilo animal with the same dosage of dye but one of the kidneys was removed half an hour after an alkaline reaction of the urine had been established, instead of after the lapse of but 12 minutes as in the previous experiment.…”
Section: Intravenous Injection Of 5 Per Cent Solution Of Sodium Bicarsupporting
confidence: 85%
“…We were unable to secure satisfactory staining of the rat's kidney after intravenous injections of azolitmin (Grtibler), with our own preparation of azolitmin or with sodium alizarin VI, dyes with which Stieglitz (7) reported success in dogs. Exitus frequently occurred soon after injection of the dyes when given in quantities too small to stain the kidneys.…”
Section: Results After In~ravenous Injectionsmentioning
confidence: 92%
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“…Harvey and Bensley,10 by means of the injection of vital dyes, and Chambers,11 by microdissection studies, have shown that the parietal cells of the gastric glands are alkaline when there is an active production of an acid gastric juice. Stieglitz 12 has recently demonstrated that the cells of the kidney tubules, which are aiding in the secretion of an acid urine and are nourished by blood which is nearly neutral, are themselves alkaline in reaction. This difference in reaction between cells and fluids may be an important phase of the mechanism for the control of the hydrogen ion concentration of the organism.…”
Section: Introductionmentioning
confidence: 99%