Histological discrimination of idiopathic inflammatory bowel disease from other types of colitis.

Abstract

We reviewed 246 colonic biopsy specimens. Biopsy specimens were fixed in formaldehyde, embedded in paraffin wax, step-sectioned at 4 jum, and stained with haematoxylin and eosin and periodic acid-Schiff. At least 10 serial sec-

The Importance of Clinicopathological Features for Differentiation Between Crohn’s Disease and Ulcerative Colitis.

“…This was in agreement with Cotran, (1999) who recorded that the onset of disease peaks between the ages of 20 -25 years, and women are affected more often than men are. Similar findings were also obtained by Seldenrijk, (1991) and Berre et al, (1995) who found that the mean age for UC was 40 years and 39 years respectively, but the opposite was detected for sex predominance as they found that men were affected more often than women. (17,18,19).…”

Morphology of colorectal lymphoid aggregates in cancer, diverticular and inflammatory bowel diseases

“…7,16,17 The increase of density in active inflammatory bowel diseases exceeds by two to four folds the aggregate proliferation seen close to inflamed diverticula. Moreover, most of aggregates in Crohn's disease and a substantial part of them in ulcerative colitis is positioned deeply in the submucosa or even transmurally.…”

Histopathological evaluation of ulcerative colitis in colonoscopic biopsies

“…Hence it is recommended that rather than individual histomorphological features, combination of these changes need to be considered before giving the diagnosis of UC. 2,23 Atypical presentation in UC is not uncommon. We noted one case with rectal sparing.…”