Histological findings in breast tissue specimens fromreduction mammoplasties

Karabela-Bouropoulou, V.; Liapi-Avgeri, G.; Iliopoulou, E.; Agnantis, Niki J.

doi:10.1016/s0344-0338(11)80427-9

Cited by 27 publications

(11 citation statements)

References 13 publications

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“…Most patients (90%) in our population had benign histologic characteristics found at the time of surgery, compared with a previously reported 85%. 7 Ninety-five percent of all proliferative lesions were found in patients older than 30 years, which correlates well with previous reports in which all specimens with atypical cells were found in patients older than 30 years. 7,8 KarabelaBouropoulou et al 7 reported a 10% risk of a woman between the ages of 30 to 40 years of harboring proliferation in their mammaplasty specimens and a 31% risk of having a proliferative lesion from the age of 40 years and older.…”

Section: Discussionsupporting

confidence: 91%

Suspicious Findings in Reduction Mammaplasty Specimens: Review of 182 Consecutive Patients

Blansfield¹,

Kukora²,

Goldhahn³

et al. 2004

Annals of Plastic Surgery

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Breast reduction mammaplasty allows examination of specimens from a seemingly healthy population for the presence of proliferative breast disease. The authors reviewed the charts of all reduction mammaplasty patients of a single surgeon over 7.5 years for age, family history, mammographic results, unilateral or bilateral nature of the procedure, and final pathologic diagnosis. Of 182 patients, 168 had bilateral and 14 had unilateral breast reductions. Ages ranged from 16 to 79 years (average and median: 37 years and 35 years respectively). Fifty-seven patients (31%) were younger than 30 years, 53 patients (29%) were between the ages 30 years and 39 years, for a total of 110 patients (60%) younger than 40 years in this study. A total of 163 patients (89%) had a diagnosis of normal breast tissue. Nineteen patients (10%) had proliferative changes: 9 patients (5%) without atypia, 5 patients (3%) with atypia, 3 patients (2%) with sclerosing adenosis, and 1 patient each (0.5%) with papillomatosis and lobular carcinoma in situ. A total of 95% of patients with proliferative changes were older than 30 years. Women ages 30 to 39 years may be at higher risk (15%) of having proliferative changes than previously reported, and histologic examination of all reduction mammaplasties is recommended.

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Section: Discussionsupporting

confidence: 91%

Suspicious Findings in Reduction Mammaplasty Specimens: Review of 182 Consecutive Patients

Blansfield¹,

Kukora²,

Goldhahn³

et al. 2004

Annals of Plastic Surgery

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“…Other reports identified a variety of pathologic changes ranging from more common proliferative lesions to rare invasive carcinomas. [1][2][3][4][5][6] In a relatively recent survey of 2,576 patients who underwent RM, 4 breast carcinomas were detected in the surgical specimens. 3 This is a lower percentage (0.16%) of malignant neoplasms than that reported by Snyderman and ❚Image 3❚ Ductal carcinoma in situ in a reduction mammaplasty specimen (H&E, ×200).…”

Section: Discussionmentioning

confidence: 99%

“…Usually only a few random sections are submitted for histologic examination. Although it has been documented that occult breast carcinomas rarely might be found in these specimens, [1][2][3][4][5][6] we are aware of only a few studies regarding the value of routine pathologic examination of RM specimens. We evaluated pathologic findings in RMs performed in our institution during an 11.5-year period.…”

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confidence: 99%

Pathologic Findings in Reduction Mammaplasty Specimens

et al. 2003

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Reduction mammaplasty (RM) is a common surgical procedure that yields a variable amount of tissue for pathologic examination. Occult breast carcinomas are detected rarely in these specimens. We evaluated the pathologic findings in RM specimens performed in our institution during an 11.5-year period (July 1989 to December 2000). A total of 560 patients who had undergone RM were identified, 503 bilateral and 57 unilateral. The average number of blocks submitted per breast was 3.9 (range, 1-23). Pathologic changes were present in 338 cases (60.4%). Unsuspected carcinomas (small invasive carcinomas, 3; ductal carcinoma in situ, 1) were found in 4 cases (0.7%). Atypical ductal and/or atypical lobular hyperplasia were identified in 8 cases (1.4%). Lesions associated with a mildly increased carcinoma risk (moderate/florid ductal hyperplasia, sclerosing adenosis, and papilloma) were identified in 52 cases (9.3%). Other findings included fibrocystic changes, fibrosis, mild ductal hyperplasia, fibroadenoma, and adenosis. Pathologic examination of RM specimens provides important clinical information and should be performed routinely.

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“…37 The increased risk for developing malignant breast disease in patients with macromastia is due to the higher volume. Decrease in volume lowers the risk to a level comparable to women with normal-sized breasts.…”

Section: Physiology and Pathophysiologymentioning

confidence: 99%

Breast Reduction and Mastopexy

Eisenmann‐Klein

2010

Plastic and Reconstructive Surgery

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Histological findings in breast tissue specimens fromreduction mammoplasties

Cited by 27 publications

References 13 publications

Suspicious Findings in Reduction Mammaplasty Specimens: Review of 182 Consecutive Patients

Suspicious Findings in Reduction Mammaplasty Specimens: Review of 182 Consecutive Patients

Pathologic Findings in Reduction Mammaplasty Specimens

Breast Reduction and Mastopexy

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