Histology of Crohn's syndrome

Presence of Granulomas in Mesenteric Lymph Nodes Is Associated with Postoperative Recurrence in Crohnʼs Disease

“…However, the rate of granulomata in MLN is close to the previously reported 20% by Williams. 43 Another reason for our lower number may be due to recognition of crypt rupture granuloma, at least for granulomas in the intestinal wall. Currently, little is known about whether the presence of granulomas in MLN is associated with the prognosis of CD, although several studies reported an association between the presence of intestinal granulomas and disease course of CD.…”

Endoscopic mucosal biopsies are useful in distinguishing granulomatous colitis due to Crohn's disease from tuberculosis

“…Conventionally accepted histological features of Crohn’s disease such as discontinuous mucosal inflammation6 8 9 and focal lesions9-11 were surprisingly also seen in the biopsy specimens of TEC. It is our suggestion that the term focally enhanced inflammation, defined as neutrophil infiltration and overrunning of crypts associated with a corresponding infiltrate of chronic inflammatory cells in the adjacent lamina propria, be more widely used for the typical focal lesions in Crohn’s disease affecting the intestines.…”

A comparative radiographic and pathological study of intestinal vaso-architecture in Crohn's disease and in ulcerative colitis

“…Williams (1964) as well as McGovern and Goulston (1968) observed obstructive vasculitis only occasionally. According to Knutson et al (1968), intimal and medial hyperplastic with narrowing of arterial lumina is a common and significant finding in Crohn's disease.…”