Histology of the Human Corpus Luteum of Early and Late Pregnancy

Abstract

of the human corpus luteum of early and late pregnancy. Acta path. microbiol. scand. Sect. A, 83: 669-677, 1975. T h e aim of this investigation has been to examine which histological parameters are of value in the age determination of the corpus luteum of pregnancy. The material comprises representative ovarian biopsies from 16 women from the 10th through 42nd week of gestation. The following histological parameters have been found useful for the age determination of the corpus luteum: 1 ) the size of the granulosa cells; 2) the number of K-cells, vacuoles and colloid inclusions in the granulosa cell layer; 3 ) the size of the theca interna cells; 4 ) the number and size of vessels in the theca interna. Furthermore, the differentiation of the corpus luteum of pregnancy from the corpus luteum of menstruation is described, and some indications for a histological age determination of the corpus luteum of pregnancy are mentioned.

Changes in blood-flow impedance of the human corpus luteum throughout the luteal phase and during early pregnancy

“…Our result of an increase in luteal blood-flow impedance after 8 weeks of gestation may be associated with luteoplacental shift. According to the literature (38)(39)(40), blood vessels are well maintained in the corpus luteum until 10 weeks of gestation, but there is an increase in venous collapse and thickness of arteriolar media with complete obliteration of the lumen after 11 weeks of gestation. Therefore, the increase in luteal-RI after 8 weeks of gestation may be due to the functional change of blood vessels.…”

Histoarchitectural Study of Corpus Luteumin Pregnant and Non-Pregnant State

“…These cells also show large vacuoles in the cytoplasm Few cells having darkly staining cytoplasm were also seen. The same type of cells were reported by Visfeldt J et.al, [4] and were called as the K cells or the dark cells. The layer towards the periphery of the granulosa lutein cells was composed of cells of smaller size known as the theca luteal cells.…”

Ovarian ectopic pregnancy: the role of complex morphopathological assay. Review and case presentation

“…Inhibin represents a protein complex which inhibits follicle-stimulating hormone synthesis [ 72 ], however it does not block the gonadotropin-releasing hormone (GnRH) synthesis [ 73 ]. This complex is present in the corpus luteum and can represent a marker in fetuses for Down syndrome when its values are abnormal [ 74 ] or for ovarian cancer [ 75 , 76 , 77 , 78 ].…”