Histopathologic Effects of Glass Ionomer Bone Cements Application to Maxillofacial Area: An Experimental Study in Rabbits

Can glass polyalkenoate (glass-ionomer) dental cements be considered bioactive? A review

“…Recent studies using rabbit models have confirmed these earlier findings. Freshly placed cements showed a small early inflammatory response, after which they were well tolerated and became fully integrated into bone with a mechanically strong attachment [ 81 ]. Demonstrating bioactivity in vitro …”

Bioceramics in ophthalmology

“…These attractive features have generated interest in other fields of medicine like otolaryngology and, more recently, maxillofacial reconstruction. Yorgancilar et al [188] tested the suitability of GIC in 16 New Zealand white rabbits, which were divided into two equal study (8 rabbits) and control (8 rabbits) groups. Experimental defects and fractures were created in the nasal bone, maxilla and zygoma in both groups and were reconstructed by GIC in the study group, whereas the rabbits in the control group were left to natural healing process.…”