Histopathologic study of epithelial components in the connective tissue wall of unilocular type of calcifying odontogenic cyst

Abstract

Histopathologic study of satellite cysts and odontogenic epithelial islands in connective tissue wall of unilocular type of calcifying odontogenic cyst (COC) was made. The material was 13 cases consisting of 3 simple unicystic COCs, 9 odontome producing COCs and 1 ameloblastomatous proliferating COC. Satellite cysts were found in 6 cases, and were histologically classified into following types: simple cystic, odontome producing and ameloblastomatous. Histologic types of satellite cysts did not coincide with those of main cystic lesions in some cases. Odontogenic epithelial islands with or without proliferating feature were found in 9 cases, and were found in all cases with satellite cysts. Melanin and melanocytes were seen in an ameloblastomatous satellite cysts of 1 of 3 pigmented COCs.

Case report of a pigmented dentigerous cyst and a review of the literature on pigmented odontogenic cysts.

“…The racial factor may play an important one in pigmented odontogenic lesions, since most patients with pigmented odontogenic lesions are Asian or Black (7,(8)(9)(10)(11)(12)(13)(14)(15). However, the limited number of cases does not give any statistical value to the data.…”

“…We have studied the occurrence and distribution of melanocytes and melanin-pigment in intra-osseous odontogenic lesions, and discuss their possible histogenesis and pathological significance in the jaw lesions (8)(9)(10)(11)(12)(13)(14)(15)(16). The present paper reports a case of dentigerous cyst with melanin-pigmented epithelial lining in the belief that this represents a not previously described component within the spectrum of odontogenic cysts.…”

Histologic Variants of Calcifying Odontogenic Cyst: A Study of 52 Cases

“…other odontogenic tumors. [23][24][25] Ameloblastomatous COC is different from true ameloblastoma arising in COC as despite ameloblastoma ex-COC, the ghost cells and dystrophic calcification can be observed within the proliferative epithelium. The coexistence of COC with odontoma is controversial.…”

Ghost cell odontogenic cyst : A rare case with literature review

“…1 The calcifying odontogenic cyst (COC) was first characterized by Gorlin et al 2 COC is now recognized as a distinct pathologic entity by the World Health Organization. 3 The COC is generally regarded as a benign lesion of odontogenic origin, which can present as a cyst or as a neoplasm. 3 COC is usually asymptomatic and may be an incidental radiographic finding.…”

“…3 The COC is generally regarded as a benign lesion of odontogenic origin, which can present as a cyst or as a neoplasm. 3 COC is usually asymptomatic and may be an incidental radiographic finding. 3 In coincidence a case of calcifying odontogenic cyst is reported with brief review of literature, in 26 years old female, which was an incidental radiographic finding, without any obvious swelling and associated symptoms.…”