Histopathological and cytological correlation of tumors of breast

Yalavarthi, Sushma; Tanikella, Ramamurti; Prabhala, Shailaja; Tallam, Uma Shankar

doi:10.4103/0975-2870.128975

Cited by 22 publications

(20 citation statements)

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“…In present study fibroadenoma was most common benign breast lesion which is in agreement with Dominguez et al, 15 Tiwari, 16 Qasim et al, 17 Srikanth 18 and Yalavarthi et al 19 In our study majority of benign breast lesions were seen within the age bracket of 10 to 40 years, which is in agreement with Khemka et al 10 (15-44 years) and Rocha et al 20 (14-40 years). However, MacIntosh et al 21 had majority of benign cases within the age bracket 27-77 years.…”

Section: Discussionsupporting

confidence: 91%

Correlation of FNAC with Histopathology of breast lesions

Risaldar¹,

Begum²,

Alvi³

2020

JDPO

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Breast cancer is a commonest maliganancy of women globally. A papable breast lump is common diagnostic dilemma to surgeons. Fine needle aspiration cytology (FNAC) is simple rapid, accurate diagnostic tool for evaluating palpable breast lumps. Mammography is other screening modality for a breast lump which is routinely used method with simple, low cost with high accuracy. Aim: To differentiate and categories the breast lesions, and to study the correlation of FNAC with histopathology of palpable breast lumps.Materials and Methods: one and half year retrospective study carried out from January 2019 to June 2020 in the department of pathology, KBNIMS, Gulbarga. FNAC and Histopathology slides were retrieved and reviewed. All the slides were observed and findings recorded. Mammography findings were retrieved and recorded.Result: The present study includes 125 cases out of which 101 cases (80.8%) were benign and 24 cases (19.2%) were malignant. Most common benign breast lesion was fibroadenoma (52.4%) and malignant lesion was infiltrating ductal carcinoma (75%). Frequencies of left breast lesions were high compare to right breast lesions. Out of 125 cases FNAC, 123 cases (98.4%) correlated with histopathology with sensitivity of 91.66%, specificity of 100%, positive predictive value (PPV) of 100%, negative predictive value (NPV) of 98% and accuracy of 98.4%.Out of 125 cases, mammography of 25 cases were retrieved with sensitivity of 87.5% and specificity of 94.11% with diagnostic accuracy of 92%. Conclusion: FNAC is a valuable diagnostic tool; provide rapid and reliable diagnosis in breast lesions.

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Section: Discussionsupporting

confidence: 91%

Correlation of FNAC with Histopathology of breast lesions

Risaldar¹,

Begum²,

Alvi³

2020

JDPO

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“…Among malignant lesions, ductal cell carcinoma was the most common, which coincide with the many authors [18,19,20]. The difference was noted in the incidence of malignant and benign lesions in various studies, which may be explained on basis of variables like duration of study period, number of cases studied, age group of patients etc.…”

Section: Malignant Lesionsupporting

confidence: 59%

“…In the series of benign breast lesions, fibroadenoma constituted the largest disease group with maximum incidence in the third decade which also observed in Sonali Saraf et al [13], Sreedevi et al [9], Dr. A. Savangan [3], Sahil I et al [2], Pinto et al [11], Chauhan N et al [14], Gupta R [15], Begun Farida et al [10] and Bhagat R et al [16]. But in other studies like Ishita P et al [17], Swapan et al [18] and Sushma et al [19] fibrocystic change was the commonest benign lesion.…”

Section: Malignant Lesionmentioning

confidence: 86%

Cytological evaluation of breast lesions with histopathological correlation in patients present with breast lump

Patel

Shah

Parikh

et al. 2019

Trop J Pathol Microbiol

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Background: Breast carcinoma is the leading cause of death with cancer in women. Management of breast lumps can be challenging in resource poor settings. Fine needle aspiration cytology of breast is an important mode of diagnosis and forms a part of triple assessment, which includes FNAC (fine needle aspiration cytology), mammography and clinical examination. Objective: To examine the cytological details in aspirated smears from lumps in the breast, to evaluate the role of FNAC in improving the quality of diagnosis by comparing with histopathological features and to separate malignant lesions that require more radical therapy from benign ones that may be conservatively managed. Methods: A prospective study is carried out on 100 patients with breast lump over a period of one year including 4 bilateral, 49 left sided and 47 right sided lesions at territory hospital, Chandkheda, Ahmedabad, Gujarat. Histopathology examination were obtained in 27 cases. All the aspirates and histopathology slides were stained with H & E stain. Results: Out of 100 cases of FNAC breast 80 cases were diagnosed as benign and 20 cases were diagnosed as malignant. Histopathological correlation was done on 27 cases and all were confirmed by FNAC. Conclusion: FNAC is a safe, simple, and costeffective outpatient procedure associated with negligible complication. And along with histopathological correlation it increases the diagnostic accuracy. That helps the clinicians for early diagnosis and specific management thus reducing morbidity and mortality.

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“…Positive predictive value in present study is 98.08%. [4] 96 100 Adetola Olubunmi Daramola, et al [8] 95.4 100 I. Yusuf et, al [25] 81 97.7 D.E.Obaseki, et al [26] 97.4 100 ShushmaYalavarthi, et al [27] 100 84…”

Section: Resultsmentioning

confidence: 99%

Analysing false negatives and false positives in cytopathology of breast masses along with cytohistopathological correlation

Patel¹,

Sinha²,

Patel³

2020

ACHR

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Introduction: Carcinoma of the breast is the leading cause of death in women due to malignancy. Approximately 1,000,000 cases occur worldwide annually. Evaluation of the breast masses is of utmost important for its timely management. Fine needle aspiration cytology is a simple and reliable diagnostic method. The present study aim ED to determine the diagnostic efficacy of the fine needle aspiration cytology along with evaluating the causes of false negative and false positive in breast cytology. Materials and Methods: The present retrospective study was conducted in G K General Hospital, Bhuj for a period of one year. Cases in which follow up histopathology was available were only included in the present study. A total 52 cases were included in the study. Results: Fine needle aspiration cytology findings and histopathology diagnoses were correlated. Statistical analysis was done. Out of the 52 cases, only one false positive and one false negative case was found. Hence, the sensitivity of the study was 98% and the positive predictive value was also 98%. Conclusion: Fine needle aspiration cytology is a reliable diagnostic method to evaluate the breast masses. A high sensitivity and a high positive predictive value proved that a positive fine needle aspiration cytology in the breast correlates very well with the corresponding final histopathology reports.

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Histopathological and cytological correlation of tumors of breast

Cited by 22 publications

References 0 publications

Correlation of FNAC with Histopathology of breast lesions

Correlation of FNAC with Histopathology of breast lesions

Cytological evaluation of breast lesions with histopathological correlation in patients present with breast lump

Analysing false negatives and false positives in cytopathology of breast masses along with cytohistopathological correlation

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