Histopathological Changes in Early Human Ectopic Pregnancy and Anatomical Considerations for Its Rupture

Abstract

Background: Implantation of blastocyst anywhere else, other than uterine cavity is considered as ectopic pregnancy. About 95% of ectopic pregnancies are implanted in the various segments of fallopian tube. Fertilization takes place in the lumen of fallopian tube, from where, aided by the ciliated columnar epithelium of the tube, the fertilized ovum makes its way to the uterine cavity and the implantation occurs. Methods: A study was carried out on 50 patients in the department of pathology, GMC Patiala.to the compare the histopathological and anatomical changes in the lining of the fallopian tube. Results: The routine Haematoxylin and Eosin stain was done and the histopathological study was done. Conclusion: It was concluded that early diagnosis and treatment before rupture still remains the main option of management.

Muscular and Vascular Fallopian Tube Morphology in Ectopic Tubal Pregnancy

“…Even in a recent article of Kaur M et al who have studied histopathological changes in early human ectopic pregnancy and anatomical consideration for its rupture, such findings have not been mentioned. [22] Whether these findings are related to hormone induced changes due to pregnancy or due to some other underlying etiology remains to be evaluated.…”