Histopathological correlation of cervical biopsy and tissue after excision in patients with precancerous lesions of the cervix

Mandić, Aljoša; Stevanović, Nemanja; Gutić, Bojana; Maričić, Slobodan; Nikin, Zoran; Šolajić, Nenad

doi:10.1007/s00404-020-05911-w

Cited by 1 publication

(1 citation statement)

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“…Сравнительный анализ гистологических заключений после первично-операционной (эксцизионной) биопсии у пациентов с ранее проведенной прицельной биопсией шейки матки показал более высокую положительную корреляцию в контексте CIN I (L-SIL) и CIN III (H-SIL) по сравнению с CIN II (H-SIL). У 1,8% пациенток c CIN III (H-SIL) по результатам прицельной биопсии гистологическое исследование материала, полученного эксцизионными методами, выявило рак шейки матки [33].…”

Section: цитология гистология иммуногистохимияunclassified

Challenges in the diagmosis of cervical pathologies

Chernov,

Tikhonovskaya,

Logvinov

et al. 2024

Bûll. sib. med.

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This review deals with the current state of affairs in the diagnosis of cervical squamous intraepithelial lesions. Transformation of classifications of cervical pathologies is considered. The role of cytological (liquid-based and conventional cytology), molecular biological (Digene Hybrid Capture test), immunohistochemical (p16INK4α, Ki-67), and histologic methods in the diagnosis of cervical lesions is discussed. Particular attention is paid to the diagnosis of human papillomavirus infection. Performance indicators of screening programs based on primary determination of human papillomavirus (HPV) DNA in comparison with common cytological methods are presented. Tropism of HPV to various parts of the cervix, which predisposes to the formation of deep multifocal lesions, as well as the influence of the physical status of HPV on the treatment strategy and risks of relapse are considered.

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Section: цитология гистология иммуногистохимияunclassified