Histopathological Features of Granular Cell Tumor

Abstract

The granular cell tumors are uncommon, mostly benign neoplasm of neural differentiation that can occur at any site of body. The diagnosis of the GCTs requires histopathological examination of the excised lesion. We present a histopathology case report of a GCT tumor in 26 year old female. Morphology of the tumor on Hematoxylin and Eosin (H&E) stained section, result of PAS stain, immunohistochemistry findings and differential diagnosis are discussed. Final report should include a comment on status of surgical margins because assessment of the surgical margins is important for GCTs as complete surgical excision is curative for almost all cases of benign GCTs.

Asymptomatic solitary nodule over the left flank

“…4 Presence of two of these criteria makes the tumour "atypical", and granular cell tumours with three or more of these criteria are classified as malignant. 5 The therapy of choice is complete excision with free surgical margins. Patients should be followed up periodically to look for recurrences.…”