Histopathological Findings and Clinical Outcomes of Patients After Laparoscopic Sleeve Gastrectomy

Abstract

Laparoscopic sleeve gastrectomy (LSG) has become an increasingly common method for surgical treatment of morbid obesity in recent years. This study aimed to evaluate the histopathological findings of gastrectomy specimens obtained in LSG and the clinical outcomes of patients. Between June 2018 and December 2019, the resected gastric samples of 170 patients with LSG underwent histopathological examination. Histopathologic examination is routinely performed on the gastric specimen that is resected during the sleeve gastrectomy for histopathologic examinations of the severity of inflammation, atrophy, intestinal metaplasia, and H. pylori infection. We found that the most common histopathological findings were chronic gastritis (58.2%), normal gastric mucosa (17.6%), and chronic active gastritis (12.4%). Patients with normal gastric histopathology after LSG lost more weight at the end of the 1st, 3rd, 6th, and 12th months than those with abnormal histopathological findings (chronic gastritis, chronic active gastritis, and edema congestion). Histopathologic examinations are extremely necessary for diagnosing lesions that may have been missed in endoscopies before sleeve gastrectomy. Many factors, such as age, sex, histopathology of the removed stomach, and H. pylori positivity, should be considered in predicting postoperative weight loss success.