ÖzetAmaç: Meme kanseri Türkiye'de ve Dünya'da kadınlarda en sık tanı alan kanser türünü oluşturmaktadır. Bu çalışmanın amacı, Tıp Fakültesinde okuyan öğrencilerin meme kanseri ve kendi kendine meme muayenesi hakkında bilgi ve tutumlarının değerlendirilmesidir. Gereç ve yöntem: Kesitsel tipteki bu çalışmaya, Pamukkale Üniversitesi Tıp Fakültesi öğrencileri dahil edildi. Çalışmaya katılan öğrencilere sosyo-demografik özellikleri içeren ve meme kanseri ve KKMM ile ilgili bilgi ve tutumdan oluşan 17 soruluk anket formu yüz yüze uygulandı. Veriler SPSS 22.0 (Statistical Package For Social Sciences) paket programıyla analiz edildi. Bulgular: Araştırmamıza 273 öğrenci katıldı. Yaş ortalaması 21±1,8 olup, %59,7'sini kız öğrenciler oluşturmaktaydı. Öğrencilerin %10,6'sının ailesinde meme kanseri öyküsü mevcuttu. Öğrencilerin %69,6'sı (n:190) kendi kendine meme muayenesi yapmayı bildiği ve %42,9'unun kendi kendine meme muayenesi yaptığı tespit edildi. Meme kanserine neden olan en önemli risk faktörleri sorgulandığında; en sık verilen cevaplar: ailede meme kanseri öyküsünün olması (%87,9), radyasyona maruziyet (%86,8) ve yaşın artması (%85,7) idi. Meme kanseri belirtileri sorgulandığında ise en sık verilen cevaplar; aksillada lenfadenopati varlığı (%79,1) ve memede kitle olması (%75,8) idi. Sonuç: Kadınlarda meme kanseri erken tanısına yönelik tarama bilincinin arttırılması ve bu taramaların düzenli yapılması için, sağlık çalışanları ve adaylarına yönelik eğitim programlarının yapılandırılması ve uygulanması gerekmektedir.

No abstract

Tempol infusion reduced local organ damage due to acute necrotizing pancreatitis in this experimental study. These findings demonstrate that tempol has protective effects on local organ damage due to acute necrotizing pancreatitis in rats.

Aims: The aim of this study was to determine whether seroma formation was affected by reduction of the potential dead space with the flap fixation method and obliteration of the axillary region in patients with breast cancer who underwent either mastectomy and axillary lymph node dissection or sentinel lymph node biopsy. A total of 105 patients with breast cancer were divided into two groups according to wound closure patterns. Patients and Methods: The operating time, postoperative pain and complications, time to drain removal, seroma formation, amount of fluid aspirated and number of aspirations were recorded prospectively. Results: No significant difference was found between groups in the rates of seroma development (P = 0.7), complication rates (P = 0.6), time to drain removal (P = 0.5), length of hospital stay (P = 0.3) or numbers of aspiration (P = 0.7). The operating time for fixation was determined to be longer than that of the classic procedure (P = 0.02). Conclusions: Reducing potential dead space with flap fixation and obliteration of the axillary region may be useful in decreasing the development of seroma in patients who have undergone mastectomy because of breast cancer. However, surgical technique must be careful, and appropriate patient follow-up must be conducted.

Orthotopic liver transplantation is a life-saving procedure for patients with end-stage liver failure. However, Acinetobacter baumannii infections and acute rejection are important causes of morbidity and mortality following transplants. Here we present a case report of a cadaveric donor liver transplantation with infectious complications detected after transplantation. The patient was a 64-year-old female. Because of non-alcoholic steatohepatitis due to hepatic insufficiency (model for end-stage liver disease (MELD): 12; Child-Pugh: 9B), liver transplantation from a cadaveric donor was performed. Following the transplantation, the patient developed a blood stream infection, urinary tract infection (UTI) and postoperative wound infection from biliary leakage. A. baumannii was isolated from blood, urine and wound cultures. Imipenem (4×500 mg), tigecycline (2×50 mg) and phosphomycin (4×4 g) were administered intravenously (IV). On the 14th day of treatment, the bile fistula closed and there was no bacterial growth in blood and urine cultures. The patient was discharged with full recovery. The duration of a transplant patient’s hospital stay, intensive care unit stay, invasive interventions, blood transfusions and immunosuppressive treatments cause an increased risk of extensively drug-resistant (XDR) A. baumannii infections, and a high mortality rate is seen despite antibiotic treatment. Phosphomycin, used in combination therapy, may be an alternative in the treatment of XDR pathogens in organ transplant patients, due to its low side effect profile and lack of interaction with immunosuppressives.