Histopathological spectrum of gastrointestinal lesions - an experience in a tertiary care centre in South India

Prasaad, Priavadhana Rajan; Rao, Bheema

doi:10.18203/2320-6012.ijrms20162302

Cited by 5 publications

(6 citation statements)

References 4 publications

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“…Among the 17 cases of duodenal biopsies in the present study result showed that all 17 were non neoplastic and the commonly observed condition was chronic nonspecific duodenitis. This result is in correlation with the study result of previous study [34].…”

Section: Total 113 100supporting

confidence: 93%

Evaluating the spectrum of histomorphological patterns on endoscopic biopsy in patients with upper gastrointestinal tract disorders

Theresa

Lavanya

Rakesh

et al. 2020

Trop J Pathol Microbiol

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Introduction: The upper gastrointestinal tract (UGT) disorders are more common complaints in clinical practice and have got high degree of mortality and morbidity. Many different types of lesions can affect the upper gastrointestinal tract and can be classified as congenital anomalies, infections, inflammation and neoplastic lesions. Material and Methods: A total of 152 cases of upper gastrointestinal tract biopsies are included in this study, out of which 113 cases were gastric biopsies, 22 cases were esophageal biopsies and the remaining 17 cases were duodenal biopsies. Present study was carried out in the Department of Pathology at Sri Venkateshwaraa Medical College Hospital and Research Centre, Puducherry for a period of one year between March 2018 and February 2019. All the biopsies were performed using fiberoptic endoscopy. Endoscopic biopsy in combination with histopathological examination plays an important role in the early diagnosis of determining UGT lesions. Also, special stains like Giemsa, Warthin starry stain was used to demonstrate Helicobacter pylori. Aim of the study is to evaluate the histomorphological patterns of upper gastrointestinal tract disorders on endoscopic biopsy and to correlate various upper gastrointestinal tract disorders in correspondence to clinical parameters. Results: It is reported among 152 cases of UGT biopsies 137 were non-neoplastic lesions and 15 were neoplastic. Commonly affected age group was 31-40 years followed by 41 to 50 years. As per the present study, males were affected more predominantly than females. Out of the 22 cases from esophageal biopsies, 16 cases showed non-neoplastic lesions and 6 were neoplastic. The most common non-neoplastic lesion was chronic nonspecific esophagitis and neoplastic lesion reported was squamous cell carcinoma. Among 113 gastric biopsies, 104 cases were non-neoplastic lesions and 9 were neoplastic lesions. Adenocarcinoma was the predominant neoplastic lesion of stomach. All the 17 duodenal biopsies showed non-neoplastic lesions.

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Section: Total 113 100supporting

confidence: 93%

Evaluating the spectrum of histomorphological patterns on endoscopic biopsy in patients with upper gastrointestinal tract disorders

Theresa

Lavanya

Rakesh

et al. 2020

Trop J Pathol Microbiol

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“…Preponderance of males with M: F ratio of 1.2:1 was noted in our study, the results reported by Patel., et al [7] and Prasaad., et al [10] also suggest similar trend (Table 3). Most common form of GI pathology was inflammatory followed by neoplastic lesions [4].…”

Section: Agesupporting

confidence: 68%

“…Our study observed a female preponderance with reversal of M: F ratio (0.6:1). These findings are in concordance with studies reported by Prasad., et al [10] (Table 5). we encountered one case (0.5%) of xanthogranulomatous cholecystitis in the present study.…”

Section: Small Intestinementioning

confidence: 97%

Histomorphology Spectrum of Gastrointestinal Lesions in A Tertiary Care Centre

Bamanikar¹,

Sankawade²,

Bamanikar³

et al. 2019

Act Scie Canbio

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Introduction: Today gastrointestinal (GI) pathology is accepted as one of the largest sub-specialties in pathology. Histopathological evaluation of GI lesions is the gold standard for providing essential diagnostic and prognostic information to clinicians for the best and timely management of each patient. Aims and Objectives:To study the pattern of gastrointestinal non-neoplastic and neoplastic lesions and the correlation between age, sex and site distribution of various lesions. Material and Methods:This is a unicentre retrospective and prospective study of 2941 patients with GI lesions over a period of four years from January 2015 to December 2018. Biopsies and resected specimens of gastrointestinal tract were fixed in 10% Formalin. These specimens were then; processed in automatic tissue processor. Routine Hematoxylin and Eosin stain and special stains, including immunohistochemical stains were done; wherever indicated. The slides were examined and the data generated from observations was used for statistical analysis.Results: Out of a total 21831 histopathology specimens received in the four years, over 17 % specimens were GIT lesions. Of the 3738 GI specimens, appendix was the most common specimen received (26.9%) followed by gastric specimens (23.2%) and small intestine specimens (18.9%). Non-neoplastic GI lesions (94.5%) were most common followed by neoplastic lesions (5.5%).Males outnumbered female patients having M: F ratio of 1.2:1. The peak incidence for non-neoplastic lesions was found in the age group of 21-40 years and that for neoplastic lesions found in the age group of 50-70 years. Appendicitis was the most common GI pathology (26.8%) followed by gastritis (21.1%). Adenocarcinoma was the most common histological malignancy (65.4%) followed by Squamous cell carcinoma (26.7%). Most common lesion of the esophagus was squamous cell carcinoma whereas adenocarcinoma was common in the colo-rectum. Conclusion:Apart from an overview of the spectrum of histopathological lesions encountered in the surgical pathology department, this study reiterates that histopathological evaluation is a valuable diagnostic tool for definitive, early diagnosis of GI lesions, which has impact on management of the neoplasia.

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“…Venkatesh, et al [2] also reported gastric biopsies to be most common (57% of total 180) GI biopsies. This is similar to study done by Prasad PR [7] and Bilal, et al [8] who observed gastric biopsies to be most common biopsy received accounting for 56% and 64.8% of total GI biopsies. In our study, among lower GI biopsies rectal biopsy was most common in all age-groups.…”

Section: Resultssupporting

confidence: 91%

A Study of Age-Wise Spectrum of Gastrointestinal Biopsies with Endoscopic Correlation a 5-Year Experience from a Tertiary Health Care Centre in North India

Siddiqui¹,

Habib²,

Durre³

et al. 2020

Int J Pathol Clin Res

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Endoscopic biopsy is a common procedure performed in the hospital for a variety of benign and malignant lesions of gastrointestinal tract. Endoscopy is incomplete without biopsy and histopathology is the gold standard for the diagnosis of endoscopically detected lesions. This study aims at analysing age-wise spectrum of gastrointestinal biopsies with their endoscopic correlation. A total of 556 endoscopic biopsy specimens from upper and lower gastrointestinal tract were studied retrospectively from

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Histopathological spectrum of gastrointestinal lesions - an experience in a tertiary care centre in South India

Cited by 5 publications

References 4 publications

Evaluating the spectrum of histomorphological patterns on endoscopic biopsy in patients with upper gastrointestinal tract disorders

Evaluating the spectrum of histomorphological patterns on endoscopic biopsy in patients with upper gastrointestinal tract disorders

Histomorphology Spectrum of Gastrointestinal Lesions in A Tertiary Care Centre

A Study of Age-Wise Spectrum of Gastrointestinal Biopsies with Endoscopic Correlation a 5-Year Experience from a Tertiary Health Care Centre in North India

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