Histopathological Study of Endometrium in Patients of Perimenopausal Age Group in a tertiary care Hospital in West Bengal

Chakraborty, Nabanita; Chunder, Rajasri; Mukherjee, Barnali; Chakraborty, Soham

doi:10.3126/ajms.v12i9.37991

Cited by 3 publications

(2 citation statements)

References 4 publications

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“…Additionally, the mean newborn length in our study was 48.8 cm, like the findings of Lo et al [27]. Incorporating the findings of Raghunath G et al [11], Salmani D et al [28], Chakraborty S et al [29], and Sirpurkar M et al [30] into the broader context of placental and neonatal research, it becomes evident that our study contributes valuable insights into the intricate relationships between placental and neonatal parameters. These findings enhance our understanding of the multifaceted factors influencing fetal development and birth outcomes.…”

Section: Bwsupporting

confidence: 85%

“…Chakraborty S. et al conducted research in Kolkata, elucidating placental morphometric parameters in normal and diabetic pregnancies. Their findings underscore the predictive value of neonatal birth weight and maternal factors in relation to placental characteristics[29]. Sirpurkar M et al conducted a study in Bhopal, shedding light on variations in placental weight among different pregnancy complications.…”

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confidence: 94%

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Morphometric Evaluation of Human Placental and Umbilical Cord for Neonatal Indices: A Cross-Sectional Study

Tankala,

Rao,

Senapati

et al. 2023

Cureus

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Background: In India, there is only limited data on studies related to umbilical cord and placental indices in newborn infants. The present study was undertaken to evaluate the morphometric analysis of placental and umbilical cord indices and their association with length, weight, and head size in newborns. Materials and methods: This was a longitudinal cross-sectional study conducted on placentas and fetal measures from 245 women who gave birth during the study period. The placental variables, umbilical cord indices, and neonatal indices were measured. The association between the parameters was done using Pearson’s correlation, and p<0.05 was considered statistically significant. Results: The placental weight (p=0.01) and placental volume (p=0.01) showed a significant positive correlation with newborn weight. The mean placental diameter was 16.32 ± 1.54 cm, and there was no significant correlation between placental diameter and infant weight (p=0.232), length (p=0.658), or head circumference (0.842). In addition, there was a significant association between placental diameter, placental volume (p=0.000), and placental weight (p=0.000). There was a significant positive correlation (p<0.05) between ponderable index and birth weight, length, and head circumference. Conclusion: Placental weight and newborn weight were significantly associated in this study. The length of the umbilical cord was found to be related to placental weight. So, placental measurements are reliable indicators for the assessment of fetal wellbeing.

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Section: Bwsupporting

confidence: 85%

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confidence: 94%

Morphometric Evaluation of Human Placental and Umbilical Cord for Neonatal Indices: A Cross-Sectional Study

Tankala,

Rao,

Senapati

et al. 2023

Cureus

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Histomorphological Study of Endometrial Biopsies of Perimenopausal Women in Abnormal Uterine Bleeding -a Study at Tertiary Care Centre

Singh¹,

Mathew²,

Diwan³

et al. 2022

ijsr

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Background: Abnormal uterine bleeding (AUB) is one of the common complaints in women in perimenopausal age group. Endometrial sampling is needed to investigate the cause of AUB. Aim: This study was conducted to evaluate the causes of AUB in perimenopausal age group and endometrial sampling by dilatation and curettage to identify various endometrial pathological patterns. Study Design: A type of prospective observational study conducted in department of pathology JMC Jhalawar. Materials And Methods: This study was done at the Department of Pathology, Jhalawar Medical College, Jhalawar during the period of one year from October 2020 to October 2021. Perimenopausal women (41-50 yrs.) with AUB who underwent dilatation and curettage were included in the study. Result: The commonest histopathological nding was secretory endometrium (38.33%) followed by proliferative endometrium (27.5%), hormonal imbalance (9.16%), simple hyperplasia without atypia (6.66%), disordered proliferative endometrium (5.83%) product of gestation (3.33%), menstrual endometrium (2.5%), chronic endometritis (1.66%) and endometrial polyp (0.83%). Endometrial carcinoma was diagnosed in 4 patients (3.33%). Conclusion: Endometrial causes of AUB evaluated by histopathological examination of curettings revealed that proliferative and secretory endometrium was the commonest diagnosis followed by hormonal imbalance.

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The range of endometrial pathologies in patients with abnormal uterine bleeding at a tertiary care center in central India

Siddiqui,

Pandey,

Chandrakar

et al. 2024

MGM J Med Sci

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Background: Endometrial disorders are among the most common gynecological conditions globally. Abnormal uterine bleeding (AUB) refers to any irregularity in the timing, volume, or pattern of menstrual blood flow. This study investigates the histopathological spectrum of endometrial changes across various age groups in patients presenting with AUB as their primary symptom. Materials and Methods: The study analyzed 226 endometrial biopsies/specimens collected over two years from patients with AUB as the main complaint. These specimens were processed, and slides stained with hematoxylin and eosin (H&E) were examined to determine the endometrial patterns. A chi-square test assessed the relationship between age and specific endometrial pathologies. Observations and Results: Most of the 226 cases were from perimenopausal women (40–49 years), representing 57% of the total, with proliferative endometrium being the most common pattern (40.9%). About 20% of the cases were in the reproductive age group (<40 years), where typical hyperplasia was the most prevalent pattern (45.7%). Additionally, 23% of the cases involved postmenopausal women (>49 years), with endometrioid carcinoma being the most frequent pattern observed. Other endometrial patterns included disordered proliferative endometrium, endometritis, endometrial polyps, Arias–Stella reaction, and progesterone effects. Conclusion: Patients with AUB present with a wide range of endometrial patterns, from normal cyclic endometrium to malignancies. Histopathological examination remains the gold standard for diagnosing AUB, showing a significant association between endometrial lesions and age.

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Histopathological Study of Endometrium in Patients of Perimenopausal Age Group in a tertiary care Hospital in West Bengal

Cited by 3 publications

References 4 publications

Morphometric Evaluation of Human Placental and Umbilical Cord for Neonatal Indices: A Cross-Sectional Study

Morphometric Evaluation of Human Placental and Umbilical Cord for Neonatal Indices: A Cross-Sectional Study

Histomorphological Study of Endometrial Biopsies of Perimenopausal Women in Abnormal Uterine Bleeding -a Study at Tertiary Care Centre

The range of endometrial pathologies in patients with abnormal uterine bleeding at a tertiary care center in central India

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