Histopathological study of the causes for failure of intrascleral prostheses in dogs and cats

Abstract

Severe corneal disease and neoplasia are the most common causes for intrascleral prosthesis failure in dogs, whereas neoplasia is the single most common cause for intrascleral prosthesis failure in cats.

Feline glaucoma—a comprehensive review

“…In the COPLOW archive, the ratio of corneoscleral shell failures to evisceration samples indicates that the failure rate for this procedure in cats approaches 15% 40 . In a recent series, recurrence of malignant intraocular neoplasia, with life‐threatening potential, was a major reason for corneoscleral shell failure, and was diagnosed in over 70% of cats that had subsequent enucleation following intra‐scleral prosthesis placement 90 …”

Surgical Treatment of Canine Glaucoma

“…In a recent study, 8.21% of evisceration samples and 38.75% of scleral shells from previously eviscerated canine globes showed evidence of intraocular tumors. 84 The same study also highlighted a high percentage of severe corneal disease (46%) among the canine scleral shells, confirming corneal ulceration and perforation among the most common complications of this procedure.…”

Equine glaucoma: Where are we now?

“…). This option should only be considered if the ocular surface and cornea are healthy, and intraocular neoplasia is not suspected (Naranjo and Dubielzig ). Evisceration surgery likely results in decreased corneal sensitivity and wound healing ability, which, combined with blindness, may lead to a markedly increased risk of corneal disease.…”

“…Placement of an intrascleral prosthesis, which involves evisceration or removal of ocular contents with preservation of corneoscleral shell (Fig 9), is another option that may be considered more cosmetic than enucleation without placement of a prosthesis (Ruoss et al 1997). This option should only be considered if the ocular surface and cornea are healthy, and intraocular neoplasia is not suspected (Naranjo and Dubielzig 2014). Evisceration surgery likely results in decreased corneal sensitivity and wound healing ability, which, combined with blindness, may lead to a markedly increased risk of corneal disease.…”