Histopathology of Endometrial Biopsies in Cases of Abnormal Uterine Bleeding- A Four Year Study

Padhye, Amruta

doi:10.18535/jmscr/v5i5.59

Cited by 3 publications

(4 citation statements)

References 5 publications

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“…Both the incidence of polyp and carcinoma was much higher in post-menopausal age group and this is in concordance with the study by Pandey A et al and Mariam Abid et al 11,16 The overall incidence of endometrial carcinoma is 2.3% and this low incidence, when compared to studies of international regions, can be attributed to the early childbearing age and multiparity of women in Indian Subcontinent, which reduces the proliferative activity of endometrium. 18…”

Section: Discussionsupporting

confidence: 89%

“…Persistent unripe follicles expose the endometrium to excessive and prolonged estrogenic action. This is slightly lower than the findings by Dangal G. 17 A noticeable incidence of exogenous hormone endometrium or disordered proliferative endometrium [14.8%] pattern was found in our study which is comparable to the Pandey A et al study and Doraiswami S et al 12,16 Similarly in our study endometritis is seen around 5.9% which is also comparable to 3.28% and 5.1% to studies done by Moghal and Doraiswami S et al respectively.…”

Section: Discussionsupporting

confidence: 84%

“…This formed one of the most common lesion [21%] accounting for endometrial bleeding in >50years age group which is comparable 27% and 30% in Mirza et al and Pandey A et al study respectively. 13,16 Endometrial hyperplasia is commonly seen in perimenopausal age group due to failure of ovulation. Persistent unripe follicles expose the endometrium to excessive and prolonged estrogenic action.…”

Section: Discussionmentioning

confidence: 99%

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Spectrum of Endometrial lesions in patients presenting with abnormal uterine bleeding

Iqbal¹,

Kambale²,

Khandelwal³

et al. 2020

IJPO

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Introduction: Most of the patients with bleeding per vaginum undergo either colposcopic evaluation or Pap smear for cervical pathology or Trans Vaginal Ultrasound and endometrial biopsy to diagnose the definite pathology affecting endometrium. This study was done to see the pattern of histopathological spectrum of endometrial biopsy and their clinical correlation in a tertiary care hospital. Materials and Methods: This was a retro-prospective study conducted at a tertiary care hospital in western Maharashtra. 1000 biopsy cases were studied. Light microscopy examination and clinical diagnoses were correlated. Results: out of 1000 patient's maximum number belonged to perimenopausal age group followed by reproductive age group and then postmenopausal age group. In 483 cases normal histopathological pattern was observed, out of which 259 cases showed proliferative phase endometrium (25.9%) and 224 cases showed secretory phase (22.4%). 104 cases showed simple (10.4%) and 43 cases (4.3%) complex hyperplasia. Exogenous hormonal effect was seen in 148 cases (14.8%). The least pattern which was observed was endometrial carcinoma, seen in only 2.3% of patients. Conclusion:The study showed that carcinoma was most common in the post-menopausal age group. This group also had the maximum frequency of atrophic endometrium and complex hyperplasia. Proliferative endometrium was recorded highest in perimenopausal age group while reproductive age group showed highest frequency of secretory type endometrium. This study is in concordance with most other conducted studies on similar parameters.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionsupporting

confidence: 84%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Spectrum of Endometrial lesions in patients presenting with abnormal uterine bleeding

Iqbal¹,

Kambale²,

Khandelwal³

et al. 2020

IJPO

View full text Add to dashboard Cite

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“…10 In this study, proliferative (30%) and secretory (19%) endometrium were the most common histopathological patterns. Similar observation was made in a study by Abdullah et al Saraswathy et al, and Amruta Padhye et al [10][11][12] In anovulatory cycle, bleeding is due to lack of progesterone possibly non-development of corpus luteum, but in ovulatory cycle, it includes luteal phase defects and irregular shedding, due to persistence corpus luteum, leading to prolonged progesterone level. The bleeding in secretory phase is characterized by regular episodes of heavy menstrual blood loss.…”

Section: Discussionsupporting

confidence: 83%

Histo-pathological pattern of endometrial biopsy in females with abnormal uterine bleeding: a retrospective study in tertiary care hospital of Haryana

Lata¹,

Sharma²,

Kaur³

et al. 2020

Int J Reprod Contracept Obstet Gynecol

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Background: This study aimed to know the various histo-pathological patterns of endometrial biopsy and their incidence in patients of AUB.Methods: Patients in the age group between 21-75 years who had presented with AUB and underwent endometrial biopsy from 1st January 2017 to 31st December 2019 were included. The endometrial biopsy specimens which were already taken from patients with AUB were scrutinized for histopathological pattern. Various patterns of histo-pathology of endometrial biopsy were noted and studied.Results: Most common age group which was affected was between 36-40 years. The endometrial biopsies and curetting’s on histopathology revealed various patterns ranging from normal endometrium to malignancy. Patterns of normal cyclical endometrium (proliferative and secretory phases) were the most common patterns.Conclusions: Evaluation of women with AUB is important around the perimenopausal age group to detect any atypical and malignant changes and intervene early. Histopathological examination in correlation to radiological findings remain the standard procedures for diagnosis.

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Spectrum of endometrial histological findings in women with abnormal uterine bleeding in mosul province via immunohistochemical technique

Al-Nuaimy

Al-Allaf

Omar

2022

1st Samarra International Conference for Pure and Applied Sciences (Sicps2021): Sicps2021

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Histopathology of Endometrial Biopsies in Cases of Abnormal Uterine Bleeding- A Four Year Study

Cited by 3 publications

References 5 publications

Spectrum of Endometrial lesions in patients presenting with abnormal uterine bleeding

Spectrum of Endometrial lesions in patients presenting with abnormal uterine bleeding

Histo-pathological pattern of endometrial biopsy in females with abnormal uterine bleeding: a retrospective study in tertiary care hospital of Haryana

Spectrum of endometrial histological findings in women with abnormal uterine bleeding in mosul province via immunohistochemical technique

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