Histopathology of Endoscopic Resection in the Gastrointestinal Tract

Optimizing histopathologic evaluation of EMR specimens of Barrett’s esophagus–related neoplasia: a randomized study of 3 specimen handling methods

“…[5][6][7] With this technique, attention must be paid to not create tension on the specimen to avoid artifacts. [7][8][9] Overextension of the tissue and placement of the pins in neoplastic areas can cause destruction of the tissue and needle artifacts and may influence the accuracy of the histopathologic diagnosis. 5 Moreover, the pinning method is more time consuming, is cumbersome, and involves the use of sharp material.…”