History of affective disorder and the experience of fatigue in rheumatoid arthritis

Jump, Rebecca L.; Fifield, Judith; Tennen, Howard; Reisine, Susan; Giuliano, Anthony J.

doi:10.1002/art.20243

Cited by 40 publications

(44 citation statements)

References 25 publications

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“…It is difficult to compare results because of differences in the use of measurement tools for pain and depressive symptoms. disease activity and duration were not correlated with fatigue, which supports the idea that even with low disease activity people with RA are fatigued (7)(8)(9)(10).…”

Section: Resultssupporting

confidence: 61%

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Low aerobic capacity and physical activity not associated with fatigue in patients with rheumatoid arthritis: A cross-sectional study

Munsterman

Takken²,

Wittink³

2013

J Rehabil Med

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Objective: To explore whether low aerobic capacity and physical activity are associated with fatigue, when controlling for age, gender, pain and depressive symptoms in persons with rheumatoid arthritis. Methods: In 60 individuals fatigue (Multidimensional Assessment of Fatigue scale; MAF), disease activity (Disease Activity Score-28; DAS28), pain, physical and psychological status (Arthritis Impact Measurement Scales 2; AIMS2), depression (Hospital Anxiety and Depression Scale; HADS), aerobic capacity and physical activity (Short Questionnaire to Assess Health-enhancing physical activity; SQUASH) were measured. Regression analysis was performed to study the variance of fatigue explained by aerobic capacity and physical activity. Results: Mean (standard deviation (SD)) age of participants was 51.8 (SD 10.4) years and 73.3% were women. Duration of disease was 10.2 (SD 0-41) years and mean disease activity score was 3.4 (SD 1.4). Mean Global Fatigue Index was 20.3 (SD 10.5). Physical function was 1.6 (SD 1.1) and psychological status 3.1 (SD 0-8) on the AIMS2. Pain score was 4.1 (SD 2.0) and median depression score was 3.2 (range 0-15). Total amount of physical activity was 176.9 (10.6-1,492.3) METhours/week and VO 2 max was 27.8 (SD 3.8) ml/kg/min. Backward multiple regression showed a statistically significant relationship with depressive symptoms only (t = 5.4, p < 0.001), which explained 33% of variance of fatigue in patients with RA. Conclusion: Depression, but not aerobic capacity or physical activity, contributed to fatigue. However, no relationship was found between aerobic capacity and fatigue.

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Section: Resultssupporting

confidence: 61%

“…Depending on the definition it is estimated that 42-93% of individuals with RA experience fatigue (7). Individuals with RA experience more frequent, as well as higher levels of, fatigue compared with the general population (3), but disease activity does not appear to be the major predictor of fatigue (7)(8)(9)(10).…”

Section: Introductionmentioning

confidence: 99%

Low aerobic capacity and physical activity not associated with fatigue in patients with rheumatoid arthritis: A cross-sectional study

Munsterman

Takken²,

Wittink³

2013

J Rehabil Med

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“…Similar fatigue scores have been reported in RA patients with the VT scale of the MOS-SF36, the MAF and MFI [2,3,7,[24][25][26][27]. In the study by Barendregt et al [27] that used the MFI there was no difference in fatigue scores between patients with primary Sjögren's syndrome and patients with RA, and both groups reported significantly more fatigue than healthy controls.…”

Section: Discussionsupporting

confidence: 76%

“…A global fatigue index (GFI) can be computed using 15 out of the 16 items and ranges from 1 (no fatigue) to 50 (severe fatigue). The MAF has been used mainly in RA [2,3,25,26]. Global assessment of fatigue-We administered a 10-point numerical Rating Scale (RS) where 0 represented "no fatigue at all" and 10 represented "fatigue as bad as it could be".…”

Section: Multidimensional Assessment Of Fatigue (Maf) [2]-this Questimentioning

confidence: 99%

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Determination of the minimal clinically important difference for seven fatigue measures in rheumatoid arthritis

Pouchot¹,

Kherani²,

Brant³

et al. 2008

Journal of Clinical Epidemiology

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Objective-To estimate the minimal clinically important difference (MCID) of seven measures of fatigue in rheumatoid arthritis.Study Design and Setting-A cross-sectional study design based on inter-individual comparisons was used. Six to eight subjects participated in a single meeting and completed seven fatigue questionnaires (nine sessions were organized and 61 subjects participated). After completion of the questionnaires, the subjects had five one-on-one 10-minute conversations with different people in the group to discuss their fatigue. After each conversation, each patient compared their fatigue to their conversational partner's on a global rating. Ratings were compared to the scores of the fatigue measures to estimate the MCID. Both non-parametric and linear regression analyses were used.Results-Non-parametric estimates for the MCID relative to "little more fatigue" tended to be smaller than those for "little less fatigue". The global MCIDs estimated by linear regression were: FSS 20.2, VT 14.8, MAF 18.7, MFI 16.6, CFS 9.9, RS 19.7, for normalized scores (0 to 100). The standardized MCIDs for the seven measures were roughly similar (0.67 to 0.76). Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. Fatigue is a non-specific subjective symptom. In the absence of an objective measurement, fatigue can only be assessed by asking the subject. The measurement properties of available instruments need to be evaluated if they are to be used clinically or in clinical trials. Among the psychometric properties, longitudinal validity (responsiveness, sensitivity to change) is one of the most important. Closely related is the minimal clinically important difference (MCID), which is defined as "the smallest difference in score in the domain of interest (fatigue) which patients perceive as beneficial and which would mandate, in the absence of troublesome side effects and excessive cost, a change in the patient's management" [9]. The MCID is essential to interpret the magnitude of longitudinal changes or differences when comparing two treatments or different group of patients. Knowledge of MCID is also essential for meaningful sample size calculations in clinical trials. NIH Public AccessThe aim of our study was to estimate the MCID of seven validated self-administered measures of fatigue in persons with RA. The fatigue instruments identified from a literature review as suitable for use in RA and studied were: the Fatigue Severity Scale (FSS) [10,11] Patients and Methods PatientsThe study was conducted at the Mary Pack Arthritis Centre, Vancouver, Canada. All participants signe...

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Measures of fatigue: Bristol Rheumatoid Arthritis Fatigue Multi‐Dimensional Questionnaire (BRAF MDQ), Bristol Rheumatoid Arthritis Fatigue Numerical Rating Scales (BRAF NRS) for Severity, Effect, and Coping, Chalder Fatigue Questionnaire (CFQ), Checklist Individual Strength (CIS20R and CIS8R), Fatigue Severity Scale (FSS), Functional Assessment Chronic Illness Therapy (Fatigue) (FACIT‐F), Multi‐Dimensional Assessment of Fatigue (MAF), Multi‐Dimensional Fatigue Inventory (MFI), Pediatric Quality Of Life (Pe

Hewlett¹,

Dures²,

Almeida³

2011

Arthritis Care & Research

330

151

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History of affective disorder and the experience of fatigue in rheumatoid arthritis

Cited by 40 publications

References 25 publications

Low aerobic capacity and physical activity not associated with fatigue in patients with rheumatoid arthritis: A cross-sectional study

Low aerobic capacity and physical activity not associated with fatigue in patients with rheumatoid arthritis: A cross-sectional study

Determination of the minimal clinically important difference for seven fatigue measures in rheumatoid arthritis

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