Objective
Myofascial trigger points (MTrPs) are focal disruptions in skeletal muscle that
can refer pain to the head and reproduce the pain patterns of tension-type headache
(TTH). The present study applied massage focused on MTrPs of subjects with TTH in a
placebo-controlled, clinical trial to assess efficacy on reducing headache pain.
Methods
Fifty-six subjects with TTH were randomized to receive 12 massage or placebo
(detuned ultrasound) sessions over six weeks, or to wait-list. Trigger point release
(TPR) massage focused on MTrPs in cervical musculature. Headache pain (frequency,
intensity and duration) was recorded in a daily headache diary. Additional outcome
measures included self-report of perceived clinical change in headache pain and
pressure-pain threshold (PPT) at MTrPs in the upper trapezius and sub-occipital
muscles.
Results
From diary recordings, group differences across time were detected in headache
frequency (p=0.026), but not for intensity or duration. Post hoc analysis
indicated headache frequency decreased from baseline for both massage (p<0.0003)
and placebo (p=0.013), but no difference was detected between massage and
placebo. Subject report of perceived clinical change was a greater reduction in headache
pain for massage than placebo or wait-list groups (p=0.002). PPT improved in all
muscles tested for massage only (all p's<0.002).
Discussion
Two findings from this study are apparent: 1) MTrPs are important components in
the treatment of TTH, and 2) TTH, like other chronic conditions, is responsive to
placebo. Clinical trials on headache that do not include a placebo group are at risk for
overestimating the specific contribution from the active intervention.