HIV-1, hepatitis B virus, and risk of liver-related mortality in the Multicenter Cohort Study (MACS)

HIV Co-Infection with Hepatotropic Viruses and Mycobacterial Tuberculosis

“…The course of chronic HBV and HIV co-infection will present with higher levels of HBV DNA and lower rates of clearance of the hepatitis Be antigen (HBeAg) [35]. HIV increases the risk of cirrhosis and end-stage liver disease in HBV coinfection [36]. In some studies, the risk of liver related mortality has been found to be 2-3 times higher in HIV/HBV co-infected patients than in HIV-mono-infected patients [37].…”

Liver transplantation in human immunodeficiency virus-positive patients

“…28,29 HBV does not appear to promote the progression of HIV, but a higher liver-related mortality rate and more rapid progression to cirrhosis have been observed in patients chronically coinfected with HIV and HBV versus patients monoinfected with HIV or HBV. 30 In comparison with the HCV coinfection-related morbidity rate, the HBV coinfection-related morbidity rate is reduced by nucleoside and nucleotide reverse-transcriptase inhibitors (lamivudine, emtricitabine, and tenofovir), which are used in cART regimens and also have anti-HBV activity.…”

La transplantation hépatique chez les patients co-infectés VIH/VHC et VIH/VHB

“…< (Figure 2). De même, le taux de mortalité est de 14,2/1 000 chez les patients co-infectés VIH/VHB, tandis qu'il n'est que de 0,8/1 000 chez les patients mono-infectés par le VHB [10]. Le carcinome hépatocellulaire ou cancer primitif du foie, est diagnostiqué à un âge plus jeune, et à un stade plus avancé chez les patients co-infectés VIH/VHB que dans la population mono-infectée, avec pour conséquence une survie plus courte [11].…”