HIV-1 incidence estimates using IgG-capture BED-enzyme immunoassay from surveillance sites of injection drug users in three cities of China

Abstract

The HIV-1 incidence in IDU in city C was stable and relatively low. In contrast, there is a high HIV-1 incidence among IDU in cities D and E. The adjusted BED-CEIA estimated incidence rates indicate clearly that interventions must be strengthened continuously in IDU, especially in two Chinese cities.

Consequences of Drug Abuse and HIV/AIDS in China: Recommendations for Integrated Care of HIV-Infected Drug Users

“…14 A longitudinal surveillance for HIV-1 incidence in three Chinese cities with prevalent drug abuse showed as high as 9.6% of HIV-1-positive incidences among IDUs (average rate 2.1% with range from 0.57% to 9.6%). 15 Another recent study in southwest China after 3-year follow-up with HIV negative IDUs reported similar rate of 2.3% of HIV incidence. 16 IDUs accounted for a little under half of the people living with HIV=AIDS in recent years, 2 but it is a predominant transmission route in seven provinces, namely Yunnan, Xinjiang, Guangxi, Guangdong, Guizhou, Sichuan, and Hunan.…”

The burden and determinants of HIV and sexually transmitted infections in a population-based sample of female sex workers in Goa, India

“…Continuous variables were converted to categories based on published studies (eg, age), or a priori categories. HIV incidence was calculated using the Centers for Disease Control and Prevention consensus formula:23…”

A Simplified Formula for Inferring HIV Incidence from Cross-Sectional Surveys Using a Test for Recent Infection

“…2,3 Their approach provides an estimate for an annual risk of infection in a hypothetical cohort, using an estimate for the true proportion, P t , of ''recent infections'' among HIV-seropositive individuals. The estimate P t is in turn derived from the proportion, P o , of seropositive individuals in a survey who test below a threshold value for normalized BED optical density (OD-n).…”